GlowPotion™ Detan Face Mask
Share
Benefits
Benefits
⚜ Penetrates deep and remove the toughest of tan from the skin
⚜ Helps even out the skin tone and prevents the appearance of dark spots & pigmentation.
⚜ Treats tanning caused due to any reason like sun, pollution, etc.
⚜ Lightens existing blemishes, pigmentation and dark spots.
⚜ Heals acne and other scars
⚜ Repairs & rejuvenates dull skin by removing signs of fatigue from the face. Brightens the complexion, and combats dullness by reviving dull and tired skin
⚜ Reveals sensationally illuminating skin.
⚜ Removes the tanning from the skin without damaging the skin barrier
⚜ Enriched with antioxidants that protect cells from the damage caused by free radicals
⚜ Reduces Acne, White heads & Black heads
⚜ Tightens skin while making it supple and soft
⚜ Removes the dead tanned skin while deep cleansing the pores to reveal the healthy layer underneath
⚜ Helps in reproducing new cells, thus giving your skin a fresh and rejuvenated look
⚜ Repairs damage caused by sun and encourages even skin tone.
⚜ Stimulates collagen production and soothes and calms the skin
⚜ Locks in the necessary quantity of moisture, giving the facial skin the glow of youth
⚜ Smoothens skin texture and provides a relaxing and pampering spa experience at your own home
Fragrance
Fragrance
How to use
How to use
⚜ Cleanse your face and neck area with a cleanser
⚜ Gently pat dry with a soft towel
⚜ Take desired quantity of this powder, make a running paste by adding Moviestar™ toner or water
⚜ Apply on the face and neck area in a circular motion and leave for 10-15 minutes
⚜ The dried face pack should not be peeled or scratched
⚜ Rinse off with normal water with light scrubbing. Water should be sprayed on the face before removing the dried face pack.
⚜ After removing the mask, an ice cube should be rolled on the skin . This helps close open pores and tighten skin. It also tones and soothes the skin.
⚜ It should not be applied on eye contour area. The skin around the eyes is very delicate and requires a different approach as provided by Moviestar™ Eye Contour Cream.
When to use
When to use
⚜ Use it weekly, as a self beauty care regimen at home.
⚜ Ideal for year round usage as its all season formula provides complete rejuvenation and detoxification
Who should use
Who should use
⚜ All skin types
⚜ For women and men.
⚜ Ideal for weekly rejuvenation and detoxification
All Ingredients
All Ingredients
Powders of Jojoba, Rosehip, Lemon Peel, Kinnu Peel, Spearmint, Fuller's Earth, Guava Leaf and Essential Oils of Ylang Ylang & Mandarin.
Care Suggestions
Care Suggestions
⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to first usage.
Dermatologically Tested
Dermatologically Tested
This product has been thoroughly tested by dermatologists and is guaranteed safe and dermatologist approved.
Country of origin
Country of origin
Bharat
Scientific Explanation
Scientific Explanation
⚪ Tanning process
Melanin is a natural pigment produced by cells called melanocytes in a process called melanogenesis. Melanocytes produce two types of melanin: pheomelanin (red) and eumelanin (very dark brown). Melanin protects the body by absorbing ultraviolet radiation. Excessive UV radiation causes sunburn along with other direct and indirect DNA damage to the skin, and the body naturally combats and seeks to repair the damage and protect the skin by creating and releasing further melanin into the skin's cells. With the production of the melanin, the skin color darkens. The tanning process can be triggered by natural sunlight.
There are two different mechanisms involved in the production of a tan by UV exposure: Firstly, UVA radiation creates oxidative stress, which in turn oxidizes existing melanin and leads to rapid darkening of the melanin. UVA may also cause melanin to be redistributed (released from melanocytes where it is already stored), but its total quantity is unchanged. Skin darkening from UVA exposure does not lead to significantly increased production of melanin or protection against sunburn. In the second process, triggered primarily by UVB, there is an increase in production of melanin (melanogenesis), which is the body's reaction to direct DNA photodamage (formation of pyrimidine dimers) from UV radiation. Melanogenesis leads to delayed tanning, and typically becomes visible two or three days after exposure.The tan that is created by increased melanogenesis typically lasts for a few weeks or months, much longer than the tan that is caused by oxidation of existing melanin, and is also actually protective against UV skin damage and sunburn, rather than simply cosmetic. Typically, it can provide a modest Sun Protection Factor (SPF) of 3, meaning that tanned skin would tolerate up to 3 times the UV exposure as pale skin. However, in order to cause true melanogenesis-tanning by means of UV exposure, some direct DNA photodamage must first be produced, and this requires UVB exposure (as present in natural sunlight, or sunlamps that produce UVB). The ultraviolet frequencies responsible for tanning are often divided into the UVA and UVB ranges.
⚪ UVA
Ultraviolet A (UVA) radiation is in the wavelength range 320 to 400 nm. It is present more uniformly throughout the day, and throughout the year, than UVB. Most UVA is not blocked by the atmosphere's ozone layer. UVA causes the release of existing melanin from the melanocytes to combine with oxygen (oxidize) to create the actual tan color in the skin. UVA is blocked less than UVB by many sunscreens, but is blocked to some degree by clothing. UVA is known both to cause DNA damage and to be carcinogenic. However, it operates not by inducing direct DNA damage, but by producing reactive oxygen species which damage DNA indirectly. UVA induces a cosmetic tan but little extra melanin protection against sun damage, sun burn, or cancer.
⚪ UVB
Ultraviolet B (UVB) radiation is in the wavelength range 280 to 320 nm. Much of this band is blocked by the Earth's ozone layer, but some penetrates. UVB:
• triggers the formation of CPD-DNA damage (direct DNA damage), which in turn induces an increased melanin production.
• is more likely to cause a sunburn than UVA as a result of overexposure. The mechanism for sunburn and increased melanogenesis is identical.Both are caused by the direct DNA damage (formation of CPDs).
• produces Vitamin D in human skin.
• is reduced by virtually all sunscreens in accordance with their SPF.
• is thought to cause the formation of moles and some types of skin cancer.
• causes skin aging (but at a slower rate than UVA).
• stimulates the production of new melanin, which leads to an increase in the dark-colored pigment within a few days.
⚪ Mechanism of de-tanning action
De-tanning works by reducing the presence of melanin pigment in the skin. To accomplish this, there are several possible mechanisms of action:
• Inhibition of the activity of tyrosinase|Inhibition of the activity of tyrosinase: The catalytic action of tyrosinase is inhibited by the de-tanning agent.
• Inhibition of the expression or activation of tyrosinase: The anti melanogenic agent causes less tyrosinase to be generated or prevents tyrosinase from being activated to its functional form.
• Scavenging of the intermediate products of melanin synthesis.
• Preventing the transfer of melanosomes to keratinocytes
⚪ Inhibition of tyrosinase
Upregulation of tyrosinase caused by tyrosinase inhibitors. Several de-tanning agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis.
Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1, PMEL17, and many other important proteins involved in the function of melanocytes. Downregulation of MITF decreases melanogenesis and is a mechanism of action of some de-tanning agents. Various signaling pathways and genetic mutations influence the expression of MITF.
⚪ MC1R receptor and cAMP
The melanocortin 1 receptor (MC1R) is a transmembrane and G-protein coupled receptor expressed in melanocytes. MC1R is an important target for the regulation of melanogenesis. Agonism of MC1R increases the ratio of eumelanin to pheomelanin and increases the generation of melanin overall.
The MC1R and cAMP signaling pathway starts with the activation of MC1R, which causes activation of adenylyl cyclase (AC), which produces cyclic adenosine monophosphate (cAMP), which activates protein kinase A (PKA), which activates by protein phosphorylation cAMP response element-binding protein (CREB), which upregulates MITF, of which CREB is a transcription factor.
Alpha-melanocyte stimulating hormone (α-MSH), beta-melanocyte stimulating hormone (β-MSH), and adrenocorticotropic hormone are endogenous agonists of MC1R.[44]: 1175 Agouti signaling protein (ASIP) appears to be the only endogenous antagonist of MC1R. Synthetic MC1R agonists have been designed, such as the peptides afamelanotide and melanotan II.
⚪ Transfer of melanosomes
Within the skin, melanocytes are present in the basal layer of the epidermis; from these, melanocytes originate dendrites that reach keratinocytes.
Melanosomes, along with the melanin they contain, are transferred from melanocytes to keratinocytes when keratinocytes are low in the epidermis. Keratinocytes carry the melanosomes with them as they move toward the surface. Keratinocytes contribute to skin pigmentation by holding the melanin originating in melanocytes and inducing melanogenesis through chemical signals directed at melanocytes. The transfer of melanosomes to keratinocytes is a necessary condition for the visible pigmentation of the skin. Blocking this transfer is a mechanism of action of some de-tanning agents.
The protease-activated receptor 2 (PAR2) is a transmembrane and G-protein coupled receptor expressed in keratinocytes and involved in melanocyte transfer. Antagonists of PAR2 inhibit the transfer of melanosomes and have de-tanning effects, while agonists of PAR2 have the opposite effect.
GlowPotion™ Detan Face Mask
Share
Benefits
Benefits
⚜ Penetrates deep and remove the toughest of tan from the skin
⚜ Helps even out the skin tone and prevents the appearance of dark spots & pigmentation.
⚜ Treats tanning caused due to any reason like sun, pollution, etc.
⚜ Lightens existing blemishes, pigmentation and dark spots.
⚜ Heals acne and other scars
⚜ Repairs & rejuvenates dull skin by removing signs of fatigue from the face. Brightens the complexion, and combats dullness by reviving dull and tired skin
⚜ Reveals sensationally illuminating skin.
⚜ Removes the tanning from the skin without damaging the skin barrier
⚜ Enriched with antioxidants that protect cells from the damage caused by free radicals
⚜ Reduces Acne, White heads & Black heads
⚜ Tightens skin while making it supple and soft
⚜ Removes the dead tanned skin while deep cleansing the pores to reveal the healthy layer underneath
⚜ Helps in reproducing new cells, thus giving your skin a fresh and rejuvenated look
⚜ Repairs damage caused by sun and encourages even skin tone.
⚜ Stimulates collagen production and soothes and calms the skin
⚜ Locks in the necessary quantity of moisture, giving the facial skin the glow of youth
⚜ Smoothens skin texture and provides a relaxing and pampering spa experience at your own home
Fragrance
Fragrance
How to use
How to use
⚜ Cleanse your face and neck area with a cleanser
⚜ Gently pat dry with a soft towel
⚜ Take desired quantity of this powder, make a running paste by adding Moviestar™ toner or water
⚜ Apply on the face and neck area in a circular motion and leave for 10-15 minutes
⚜ The dried face pack should not be peeled or scratched
⚜ Rinse off with normal water with light scrubbing. Water should be sprayed on the face before removing the dried face pack.
⚜ After removing the mask, an ice cube should be rolled on the skin . This helps close open pores and tighten skin. It also tones and soothes the skin.
⚜ It should not be applied on eye contour area. The skin around the eyes is very delicate and requires a different approach as provided by Moviestar™ Eye Contour Cream.
When to use
When to use
⚜ Use it weekly, as a self beauty care regimen at home.
⚜ Ideal for year round usage as its all season formula provides complete rejuvenation and detoxification
Who should use
Who should use
⚜ All skin types
⚜ For women and men.
⚜ Ideal for weekly rejuvenation and detoxification
All Ingredients
All Ingredients
Powders of Jojoba, Rosehip, Lemon Peel, Kinnu Peel, Spearmint, Fuller's Earth, Guava Leaf and Essential Oils of Ylang Ylang & Mandarin.
Care Suggestions
Care Suggestions
⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to first usage.
Dermatologically Tested
Dermatologically Tested
This product has been thoroughly tested by dermatologists and is guaranteed safe and dermatologist approved.
Country of origin
Country of origin
Bharat
Scientific Explanation
Scientific Explanation
⚪ Tanning process
Melanin is a natural pigment produced by cells called melanocytes in a process called melanogenesis. Melanocytes produce two types of melanin: pheomelanin (red) and eumelanin (very dark brown). Melanin protects the body by absorbing ultraviolet radiation. Excessive UV radiation causes sunburn along with other direct and indirect DNA damage to the skin, and the body naturally combats and seeks to repair the damage and protect the skin by creating and releasing further melanin into the skin's cells. With the production of the melanin, the skin color darkens. The tanning process can be triggered by natural sunlight.
There are two different mechanisms involved in the production of a tan by UV exposure: Firstly, UVA radiation creates oxidative stress, which in turn oxidizes existing melanin and leads to rapid darkening of the melanin. UVA may also cause melanin to be redistributed (released from melanocytes where it is already stored), but its total quantity is unchanged. Skin darkening from UVA exposure does not lead to significantly increased production of melanin or protection against sunburn. In the second process, triggered primarily by UVB, there is an increase in production of melanin (melanogenesis), which is the body's reaction to direct DNA photodamage (formation of pyrimidine dimers) from UV radiation. Melanogenesis leads to delayed tanning, and typically becomes visible two or three days after exposure.The tan that is created by increased melanogenesis typically lasts for a few weeks or months, much longer than the tan that is caused by oxidation of existing melanin, and is also actually protective against UV skin damage and sunburn, rather than simply cosmetic. Typically, it can provide a modest Sun Protection Factor (SPF) of 3, meaning that tanned skin would tolerate up to 3 times the UV exposure as pale skin. However, in order to cause true melanogenesis-tanning by means of UV exposure, some direct DNA photodamage must first be produced, and this requires UVB exposure (as present in natural sunlight, or sunlamps that produce UVB). The ultraviolet frequencies responsible for tanning are often divided into the UVA and UVB ranges.
⚪ UVA
Ultraviolet A (UVA) radiation is in the wavelength range 320 to 400 nm. It is present more uniformly throughout the day, and throughout the year, than UVB. Most UVA is not blocked by the atmosphere's ozone layer. UVA causes the release of existing melanin from the melanocytes to combine with oxygen (oxidize) to create the actual tan color in the skin. UVA is blocked less than UVB by many sunscreens, but is blocked to some degree by clothing. UVA is known both to cause DNA damage and to be carcinogenic. However, it operates not by inducing direct DNA damage, but by producing reactive oxygen species which damage DNA indirectly. UVA induces a cosmetic tan but little extra melanin protection against sun damage, sun burn, or cancer.
⚪ UVB
Ultraviolet B (UVB) radiation is in the wavelength range 280 to 320 nm. Much of this band is blocked by the Earth's ozone layer, but some penetrates. UVB:
• triggers the formation of CPD-DNA damage (direct DNA damage), which in turn induces an increased melanin production.
• is more likely to cause a sunburn than UVA as a result of overexposure. The mechanism for sunburn and increased melanogenesis is identical.Both are caused by the direct DNA damage (formation of CPDs).
• produces Vitamin D in human skin.
• is reduced by virtually all sunscreens in accordance with their SPF.
• is thought to cause the formation of moles and some types of skin cancer.
• causes skin aging (but at a slower rate than UVA).
• stimulates the production of new melanin, which leads to an increase in the dark-colored pigment within a few days.
⚪ Mechanism of de-tanning action
De-tanning works by reducing the presence of melanin pigment in the skin. To accomplish this, there are several possible mechanisms of action:
• Inhibition of the activity of tyrosinase|Inhibition of the activity of tyrosinase: The catalytic action of tyrosinase is inhibited by the de-tanning agent.
• Inhibition of the expression or activation of tyrosinase: The anti melanogenic agent causes less tyrosinase to be generated or prevents tyrosinase from being activated to its functional form.
• Scavenging of the intermediate products of melanin synthesis.
• Preventing the transfer of melanosomes to keratinocytes
⚪ Inhibition of tyrosinase
Upregulation of tyrosinase caused by tyrosinase inhibitors. Several de-tanning agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis.
Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1, PMEL17, and many other important proteins involved in the function of melanocytes. Downregulation of MITF decreases melanogenesis and is a mechanism of action of some de-tanning agents. Various signaling pathways and genetic mutations influence the expression of MITF.
⚪ MC1R receptor and cAMP
The melanocortin 1 receptor (MC1R) is a transmembrane and G-protein coupled receptor expressed in melanocytes. MC1R is an important target for the regulation of melanogenesis. Agonism of MC1R increases the ratio of eumelanin to pheomelanin and increases the generation of melanin overall.
The MC1R and cAMP signaling pathway starts with the activation of MC1R, which causes activation of adenylyl cyclase (AC), which produces cyclic adenosine monophosphate (cAMP), which activates protein kinase A (PKA), which activates by protein phosphorylation cAMP response element-binding protein (CREB), which upregulates MITF, of which CREB is a transcription factor.
Alpha-melanocyte stimulating hormone (α-MSH), beta-melanocyte stimulating hormone (β-MSH), and adrenocorticotropic hormone are endogenous agonists of MC1R.[44]: 1175 Agouti signaling protein (ASIP) appears to be the only endogenous antagonist of MC1R. Synthetic MC1R agonists have been designed, such as the peptides afamelanotide and melanotan II.
⚪ Transfer of melanosomes
Within the skin, melanocytes are present in the basal layer of the epidermis; from these, melanocytes originate dendrites that reach keratinocytes.
Melanosomes, along with the melanin they contain, are transferred from melanocytes to keratinocytes when keratinocytes are low in the epidermis. Keratinocytes carry the melanosomes with them as they move toward the surface. Keratinocytes contribute to skin pigmentation by holding the melanin originating in melanocytes and inducing melanogenesis through chemical signals directed at melanocytes. The transfer of melanosomes to keratinocytes is a necessary condition for the visible pigmentation of the skin. Blocking this transfer is a mechanism of action of some de-tanning agents.
The protease-activated receptor 2 (PAR2) is a transmembrane and G-protein coupled receptor expressed in keratinocytes and involved in melanocyte transfer. Antagonists of PAR2 inhibit the transfer of melanosomes and have de-tanning effects, while agonists of PAR2 have the opposite effect.
GlowPotion™ Detan Face Mask
Share
Benefits
Benefits
⚜ Penetrates deep and remove the toughest of tan from the skin
⚜ Helps even out the skin tone and prevents the appearance of dark spots & pigmentation.
⚜ Treats tanning caused due to any reason like sun, pollution, etc.
⚜ Lightens existing blemishes, pigmentation and dark spots.
⚜ Heals acne and other scars
⚜ Repairs & rejuvenates dull skin by removing signs of fatigue from the face. Brightens the complexion, and combats dullness by reviving dull and tired skin
⚜ Reveals sensationally illuminating skin.
⚜ Removes the tanning from the skin without damaging the skin barrier
⚜ Enriched with antioxidants that protect cells from the damage caused by free radicals
⚜ Reduces Acne, White heads & Black heads
⚜ Tightens skin while making it supple and soft
⚜ Removes the dead tanned skin while deep cleansing the pores to reveal the healthy layer underneath
⚜ Helps in reproducing new cells, thus giving your skin a fresh and rejuvenated look
⚜ Repairs damage caused by sun and encourages even skin tone.
⚜ Stimulates collagen production and soothes and calms the skin
⚜ Locks in the necessary quantity of moisture, giving the facial skin the glow of youth
⚜ Smoothens skin texture and provides a relaxing and pampering spa experience at your own home
Fragrance
Fragrance
How to use
How to use
⚜ Cleanse your face and neck area with a cleanser
⚜ Gently pat dry with a soft towel
⚜ Take desired quantity of this powder, make a running paste by adding Moviestar™ toner or water
⚜ Apply on the face and neck area in a circular motion and leave for 10-15 minutes
⚜ The dried face pack should not be peeled or scratched
⚜ Rinse off with normal water with light scrubbing. Water should be sprayed on the face before removing the dried face pack.
⚜ After removing the mask, an ice cube should be rolled on the skin . This helps close open pores and tighten skin. It also tones and soothes the skin.
⚜ It should not be applied on eye contour area. The skin around the eyes is very delicate and requires a different approach as provided by Moviestar™ Eye Contour Cream.
When to use
When to use
⚜ Use it weekly, as a self beauty care regimen at home.
⚜ Ideal for year round usage as its all season formula provides complete rejuvenation and detoxification
Who should use
Who should use
⚜ All skin types
⚜ For women and men.
⚜ Ideal for weekly rejuvenation and detoxification
All Ingredients
All Ingredients
Powders of Jojoba, Rosehip, Lemon Peel, Kinnu Peel, Spearmint, Fuller's Earth, Guava Leaf and Essential Oils of Ylang Ylang & Mandarin.
Care Suggestions
Care Suggestions
⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to first usage.
Dermatologically Tested
Dermatologically Tested
This product has been thoroughly tested by dermatologists and is guaranteed safe and dermatologist approved.
Country of origin
Country of origin
Bharat
Scientific Explanation
Scientific Explanation
⚪ Tanning process
Melanin is a natural pigment produced by cells called melanocytes in a process called melanogenesis. Melanocytes produce two types of melanin: pheomelanin (red) and eumelanin (very dark brown). Melanin protects the body by absorbing ultraviolet radiation. Excessive UV radiation causes sunburn along with other direct and indirect DNA damage to the skin, and the body naturally combats and seeks to repair the damage and protect the skin by creating and releasing further melanin into the skin's cells. With the production of the melanin, the skin color darkens. The tanning process can be triggered by natural sunlight.
There are two different mechanisms involved in the production of a tan by UV exposure: Firstly, UVA radiation creates oxidative stress, which in turn oxidizes existing melanin and leads to rapid darkening of the melanin. UVA may also cause melanin to be redistributed (released from melanocytes where it is already stored), but its total quantity is unchanged. Skin darkening from UVA exposure does not lead to significantly increased production of melanin or protection against sunburn. In the second process, triggered primarily by UVB, there is an increase in production of melanin (melanogenesis), which is the body's reaction to direct DNA photodamage (formation of pyrimidine dimers) from UV radiation. Melanogenesis leads to delayed tanning, and typically becomes visible two or three days after exposure.The tan that is created by increased melanogenesis typically lasts for a few weeks or months, much longer than the tan that is caused by oxidation of existing melanin, and is also actually protective against UV skin damage and sunburn, rather than simply cosmetic. Typically, it can provide a modest Sun Protection Factor (SPF) of 3, meaning that tanned skin would tolerate up to 3 times the UV exposure as pale skin. However, in order to cause true melanogenesis-tanning by means of UV exposure, some direct DNA photodamage must first be produced, and this requires UVB exposure (as present in natural sunlight, or sunlamps that produce UVB). The ultraviolet frequencies responsible for tanning are often divided into the UVA and UVB ranges.
⚪ UVA
Ultraviolet A (UVA) radiation is in the wavelength range 320 to 400 nm. It is present more uniformly throughout the day, and throughout the year, than UVB. Most UVA is not blocked by the atmosphere's ozone layer. UVA causes the release of existing melanin from the melanocytes to combine with oxygen (oxidize) to create the actual tan color in the skin. UVA is blocked less than UVB by many sunscreens, but is blocked to some degree by clothing. UVA is known both to cause DNA damage and to be carcinogenic. However, it operates not by inducing direct DNA damage, but by producing reactive oxygen species which damage DNA indirectly. UVA induces a cosmetic tan but little extra melanin protection against sun damage, sun burn, or cancer.
⚪ UVB
Ultraviolet B (UVB) radiation is in the wavelength range 280 to 320 nm. Much of this band is blocked by the Earth's ozone layer, but some penetrates. UVB:
• triggers the formation of CPD-DNA damage (direct DNA damage), which in turn induces an increased melanin production.
• is more likely to cause a sunburn than UVA as a result of overexposure. The mechanism for sunburn and increased melanogenesis is identical.Both are caused by the direct DNA damage (formation of CPDs).
• produces Vitamin D in human skin.
• is reduced by virtually all sunscreens in accordance with their SPF.
• is thought to cause the formation of moles and some types of skin cancer.
• causes skin aging (but at a slower rate than UVA).
• stimulates the production of new melanin, which leads to an increase in the dark-colored pigment within a few days.
⚪ Mechanism of de-tanning action
De-tanning works by reducing the presence of melanin pigment in the skin. To accomplish this, there are several possible mechanisms of action:
• Inhibition of the activity of tyrosinase|Inhibition of the activity of tyrosinase: The catalytic action of tyrosinase is inhibited by the de-tanning agent.
• Inhibition of the expression or activation of tyrosinase: The anti melanogenic agent causes less tyrosinase to be generated or prevents tyrosinase from being activated to its functional form.
• Scavenging of the intermediate products of melanin synthesis.
• Preventing the transfer of melanosomes to keratinocytes
⚪ Inhibition of tyrosinase
Upregulation of tyrosinase caused by tyrosinase inhibitors. Several de-tanning agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis.
Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1, PMEL17, and many other important proteins involved in the function of melanocytes. Downregulation of MITF decreases melanogenesis and is a mechanism of action of some de-tanning agents. Various signaling pathways and genetic mutations influence the expression of MITF.
⚪ MC1R receptor and cAMP
The melanocortin 1 receptor (MC1R) is a transmembrane and G-protein coupled receptor expressed in melanocytes. MC1R is an important target for the regulation of melanogenesis. Agonism of MC1R increases the ratio of eumelanin to pheomelanin and increases the generation of melanin overall.
The MC1R and cAMP signaling pathway starts with the activation of MC1R, which causes activation of adenylyl cyclase (AC), which produces cyclic adenosine monophosphate (cAMP), which activates protein kinase A (PKA), which activates by protein phosphorylation cAMP response element-binding protein (CREB), which upregulates MITF, of which CREB is a transcription factor.
Alpha-melanocyte stimulating hormone (α-MSH), beta-melanocyte stimulating hormone (β-MSH), and adrenocorticotropic hormone are endogenous agonists of MC1R.[44]: 1175 Agouti signaling protein (ASIP) appears to be the only endogenous antagonist of MC1R. Synthetic MC1R agonists have been designed, such as the peptides afamelanotide and melanotan II.
⚪ Transfer of melanosomes
Within the skin, melanocytes are present in the basal layer of the epidermis; from these, melanocytes originate dendrites that reach keratinocytes.
Melanosomes, along with the melanin they contain, are transferred from melanocytes to keratinocytes when keratinocytes are low in the epidermis. Keratinocytes carry the melanosomes with them as they move toward the surface. Keratinocytes contribute to skin pigmentation by holding the melanin originating in melanocytes and inducing melanogenesis through chemical signals directed at melanocytes. The transfer of melanosomes to keratinocytes is a necessary condition for the visible pigmentation of the skin. Blocking this transfer is a mechanism of action of some de-tanning agents.
The protease-activated receptor 2 (PAR2) is a transmembrane and G-protein coupled receptor expressed in keratinocytes and involved in melanocyte transfer. Antagonists of PAR2 inhibit the transfer of melanosomes and have de-tanning effects, while agonists of PAR2 have the opposite effect.
GlowPotion™ Detan Face Mask
Share
Benefits
Benefits
⚜ Penetrates deep and remove the toughest of tan from the skin
⚜ Helps even out the skin tone and prevents the appearance of dark spots & pigmentation.
⚜ Treats tanning caused due to any reason like sun, pollution, etc.
⚜ Lightens existing blemishes, pigmentation and dark spots.
⚜ Heals acne and other scars
⚜ Repairs & rejuvenates dull skin by removing signs of fatigue from the face. Brightens the complexion, and combats dullness by reviving dull and tired skin
⚜ Reveals sensationally illuminating skin.
⚜ Removes the tanning from the skin without damaging the skin barrier
⚜ Enriched with antioxidants that protect cells from the damage caused by free radicals
⚜ Reduces Acne, White heads & Black heads
⚜ Tightens skin while making it supple and soft
⚜ Removes the dead tanned skin while deep cleansing the pores to reveal the healthy layer underneath
⚜ Helps in reproducing new cells, thus giving your skin a fresh and rejuvenated look
⚜ Repairs damage caused by sun and encourages even skin tone.
⚜ Stimulates collagen production and soothes and calms the skin
⚜ Locks in the necessary quantity of moisture, giving the facial skin the glow of youth
⚜ Smoothens skin texture and provides a relaxing and pampering spa experience at your own home
Fragrance
Fragrance
How to use
How to use
⚜ Cleanse your face and neck area with a cleanser
⚜ Gently pat dry with a soft towel
⚜ Take desired quantity of this powder, make a running paste by adding Moviestar™ toner or water
⚜ Apply on the face and neck area in a circular motion and leave for 10-15 minutes
⚜ The dried face pack should not be peeled or scratched
⚜ Rinse off with normal water with light scrubbing. Water should be sprayed on the face before removing the dried face pack.
⚜ After removing the mask, an ice cube should be rolled on the skin . This helps close open pores and tighten skin. It also tones and soothes the skin.
⚜ It should not be applied on eye contour area. The skin around the eyes is very delicate and requires a different approach as provided by Moviestar™ Eye Contour Cream.
When to use
When to use
⚜ Use it weekly, as a self beauty care regimen at home.
⚜ Ideal for year round usage as its all season formula provides complete rejuvenation and detoxification
Who should use
Who should use
⚜ All skin types
⚜ For women and men.
⚜ Ideal for weekly rejuvenation and detoxification
All Ingredients
All Ingredients
Powders of Jojoba, Rosehip, Lemon Peel, Kinnu Peel, Spearmint, Fuller's Earth, Guava Leaf and Essential Oils of Ylang Ylang & Mandarin.
Care Suggestions
Care Suggestions
⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to first usage.
Dermatologically Tested
Dermatologically Tested
This product has been thoroughly tested by dermatologists and is guaranteed safe and dermatologist approved.
Country of origin
Country of origin
Bharat
Scientific Explanation
Scientific Explanation
⚪ Tanning process
Melanin is a natural pigment produced by cells called melanocytes in a process called melanogenesis. Melanocytes produce two types of melanin: pheomelanin (red) and eumelanin (very dark brown). Melanin protects the body by absorbing ultraviolet radiation. Excessive UV radiation causes sunburn along with other direct and indirect DNA damage to the skin, and the body naturally combats and seeks to repair the damage and protect the skin by creating and releasing further melanin into the skin's cells. With the production of the melanin, the skin color darkens. The tanning process can be triggered by natural sunlight.
There are two different mechanisms involved in the production of a tan by UV exposure: Firstly, UVA radiation creates oxidative stress, which in turn oxidizes existing melanin and leads to rapid darkening of the melanin. UVA may also cause melanin to be redistributed (released from melanocytes where it is already stored), but its total quantity is unchanged. Skin darkening from UVA exposure does not lead to significantly increased production of melanin or protection against sunburn. In the second process, triggered primarily by UVB, there is an increase in production of melanin (melanogenesis), which is the body's reaction to direct DNA photodamage (formation of pyrimidine dimers) from UV radiation. Melanogenesis leads to delayed tanning, and typically becomes visible two or three days after exposure.The tan that is created by increased melanogenesis typically lasts for a few weeks or months, much longer than the tan that is caused by oxidation of existing melanin, and is also actually protective against UV skin damage and sunburn, rather than simply cosmetic. Typically, it can provide a modest Sun Protection Factor (SPF) of 3, meaning that tanned skin would tolerate up to 3 times the UV exposure as pale skin. However, in order to cause true melanogenesis-tanning by means of UV exposure, some direct DNA photodamage must first be produced, and this requires UVB exposure (as present in natural sunlight, or sunlamps that produce UVB). The ultraviolet frequencies responsible for tanning are often divided into the UVA and UVB ranges.
⚪ UVA
Ultraviolet A (UVA) radiation is in the wavelength range 320 to 400 nm. It is present more uniformly throughout the day, and throughout the year, than UVB. Most UVA is not blocked by the atmosphere's ozone layer. UVA causes the release of existing melanin from the melanocytes to combine with oxygen (oxidize) to create the actual tan color in the skin. UVA is blocked less than UVB by many sunscreens, but is blocked to some degree by clothing. UVA is known both to cause DNA damage and to be carcinogenic. However, it operates not by inducing direct DNA damage, but by producing reactive oxygen species which damage DNA indirectly. UVA induces a cosmetic tan but little extra melanin protection against sun damage, sun burn, or cancer.
⚪ UVB
Ultraviolet B (UVB) radiation is in the wavelength range 280 to 320 nm. Much of this band is blocked by the Earth's ozone layer, but some penetrates. UVB:
• triggers the formation of CPD-DNA damage (direct DNA damage), which in turn induces an increased melanin production.
• is more likely to cause a sunburn than UVA as a result of overexposure. The mechanism for sunburn and increased melanogenesis is identical.Both are caused by the direct DNA damage (formation of CPDs).
• produces Vitamin D in human skin.
• is reduced by virtually all sunscreens in accordance with their SPF.
• is thought to cause the formation of moles and some types of skin cancer.
• causes skin aging (but at a slower rate than UVA).
• stimulates the production of new melanin, which leads to an increase in the dark-colored pigment within a few days.
⚪ Mechanism of de-tanning action
De-tanning works by reducing the presence of melanin pigment in the skin. To accomplish this, there are several possible mechanisms of action:
• Inhibition of the activity of tyrosinase|Inhibition of the activity of tyrosinase: The catalytic action of tyrosinase is inhibited by the de-tanning agent.
• Inhibition of the expression or activation of tyrosinase: The anti melanogenic agent causes less tyrosinase to be generated or prevents tyrosinase from being activated to its functional form.
• Scavenging of the intermediate products of melanin synthesis.
• Preventing the transfer of melanosomes to keratinocytes
⚪ Inhibition of tyrosinase
Upregulation of tyrosinase caused by tyrosinase inhibitors. Several de-tanning agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis.
Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1, PMEL17, and many other important proteins involved in the function of melanocytes. Downregulation of MITF decreases melanogenesis and is a mechanism of action of some de-tanning agents. Various signaling pathways and genetic mutations influence the expression of MITF.
⚪ MC1R receptor and cAMP
The melanocortin 1 receptor (MC1R) is a transmembrane and G-protein coupled receptor expressed in melanocytes. MC1R is an important target for the regulation of melanogenesis. Agonism of MC1R increases the ratio of eumelanin to pheomelanin and increases the generation of melanin overall.
The MC1R and cAMP signaling pathway starts with the activation of MC1R, which causes activation of adenylyl cyclase (AC), which produces cyclic adenosine monophosphate (cAMP), which activates protein kinase A (PKA), which activates by protein phosphorylation cAMP response element-binding protein (CREB), which upregulates MITF, of which CREB is a transcription factor.
Alpha-melanocyte stimulating hormone (α-MSH), beta-melanocyte stimulating hormone (β-MSH), and adrenocorticotropic hormone are endogenous agonists of MC1R.[44]: 1175 Agouti signaling protein (ASIP) appears to be the only endogenous antagonist of MC1R. Synthetic MC1R agonists have been designed, such as the peptides afamelanotide and melanotan II.
⚪ Transfer of melanosomes
Within the skin, melanocytes are present in the basal layer of the epidermis; from these, melanocytes originate dendrites that reach keratinocytes.
Melanosomes, along with the melanin they contain, are transferred from melanocytes to keratinocytes when keratinocytes are low in the epidermis. Keratinocytes carry the melanosomes with them as they move toward the surface. Keratinocytes contribute to skin pigmentation by holding the melanin originating in melanocytes and inducing melanogenesis through chemical signals directed at melanocytes. The transfer of melanosomes to keratinocytes is a necessary condition for the visible pigmentation of the skin. Blocking this transfer is a mechanism of action of some de-tanning agents.
The protease-activated receptor 2 (PAR2) is a transmembrane and G-protein coupled receptor expressed in keratinocytes and involved in melanocyte transfer. Antagonists of PAR2 inhibit the transfer of melanosomes and have de-tanning effects, while agonists of PAR2 have the opposite effect.
GlowPotion™ Detan Face Mask
Share
Benefits
Benefits
⚜ Penetrates deep and remove the toughest of tan from the skin
⚜ Helps even out the skin tone and prevents the appearance of dark spots & pigmentation.
⚜ Treats tanning caused due to any reason like sun, pollution, etc.
⚜ Lightens existing blemishes, pigmentation and dark spots.
⚜ Heals acne and other scars
⚜ Repairs & rejuvenates dull skin by removing signs of fatigue from the face. Brightens the complexion, and combats dullness by reviving dull and tired skin
⚜ Reveals sensationally illuminating skin.
⚜ Removes the tanning from the skin without damaging the skin barrier
⚜ Enriched with antioxidants that protect cells from the damage caused by free radicals
⚜ Reduces Acne, White heads & Black heads
⚜ Tightens skin while making it supple and soft
⚜ Removes the dead tanned skin while deep cleansing the pores to reveal the healthy layer underneath
⚜ Helps in reproducing new cells, thus giving your skin a fresh and rejuvenated look
⚜ Repairs damage caused by sun and encourages even skin tone.
⚜ Stimulates collagen production and soothes and calms the skin
⚜ Locks in the necessary quantity of moisture, giving the facial skin the glow of youth
⚜ Smoothens skin texture and provides a relaxing and pampering spa experience at your own home
Fragrance
Fragrance
How to use
How to use
⚜ Cleanse your face and neck area with a cleanser
⚜ Gently pat dry with a soft towel
⚜ Take desired quantity of this powder, make a running paste by adding Moviestar™ toner or water
⚜ Apply on the face and neck area in a circular motion and leave for 10-15 minutes
⚜ The dried face pack should not be peeled or scratched
⚜ Rinse off with normal water with light scrubbing. Water should be sprayed on the face before removing the dried face pack.
⚜ After removing the mask, an ice cube should be rolled on the skin . This helps close open pores and tighten skin. It also tones and soothes the skin.
⚜ It should not be applied on eye contour area. The skin around the eyes is very delicate and requires a different approach as provided by Moviestar™ Eye Contour Cream.
When to use
When to use
⚜ Use it weekly, as a self beauty care regimen at home.
⚜ Ideal for year round usage as its all season formula provides complete rejuvenation and detoxification
Who should use
Who should use
⚜ All skin types
⚜ For women and men.
⚜ Ideal for weekly rejuvenation and detoxification
All Ingredients
All Ingredients
Powders of Jojoba, Rosehip, Lemon Peel, Kinnu Peel, Spearmint, Fuller's Earth, Guava Leaf and Essential Oils of Ylang Ylang & Mandarin.
Care Suggestions
Care Suggestions
⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to first usage.
Dermatologically Tested
Dermatologically Tested
This product has been thoroughly tested by dermatologists and is guaranteed safe and dermatologist approved.
Country of origin
Country of origin
Bharat
Scientific Explanation
Scientific Explanation
⚪ Tanning process
Melanin is a natural pigment produced by cells called melanocytes in a process called melanogenesis. Melanocytes produce two types of melanin: pheomelanin (red) and eumelanin (very dark brown). Melanin protects the body by absorbing ultraviolet radiation. Excessive UV radiation causes sunburn along with other direct and indirect DNA damage to the skin, and the body naturally combats and seeks to repair the damage and protect the skin by creating and releasing further melanin into the skin's cells. With the production of the melanin, the skin color darkens. The tanning process can be triggered by natural sunlight.
There are two different mechanisms involved in the production of a tan by UV exposure: Firstly, UVA radiation creates oxidative stress, which in turn oxidizes existing melanin and leads to rapid darkening of the melanin. UVA may also cause melanin to be redistributed (released from melanocytes where it is already stored), but its total quantity is unchanged. Skin darkening from UVA exposure does not lead to significantly increased production of melanin or protection against sunburn. In the second process, triggered primarily by UVB, there is an increase in production of melanin (melanogenesis), which is the body's reaction to direct DNA photodamage (formation of pyrimidine dimers) from UV radiation. Melanogenesis leads to delayed tanning, and typically becomes visible two or three days after exposure.The tan that is created by increased melanogenesis typically lasts for a few weeks or months, much longer than the tan that is caused by oxidation of existing melanin, and is also actually protective against UV skin damage and sunburn, rather than simply cosmetic. Typically, it can provide a modest Sun Protection Factor (SPF) of 3, meaning that tanned skin would tolerate up to 3 times the UV exposure as pale skin. However, in order to cause true melanogenesis-tanning by means of UV exposure, some direct DNA photodamage must first be produced, and this requires UVB exposure (as present in natural sunlight, or sunlamps that produce UVB). The ultraviolet frequencies responsible for tanning are often divided into the UVA and UVB ranges.
⚪ UVA
Ultraviolet A (UVA) radiation is in the wavelength range 320 to 400 nm. It is present more uniformly throughout the day, and throughout the year, than UVB. Most UVA is not blocked by the atmosphere's ozone layer. UVA causes the release of existing melanin from the melanocytes to combine with oxygen (oxidize) to create the actual tan color in the skin. UVA is blocked less than UVB by many sunscreens, but is blocked to some degree by clothing. UVA is known both to cause DNA damage and to be carcinogenic. However, it operates not by inducing direct DNA damage, but by producing reactive oxygen species which damage DNA indirectly. UVA induces a cosmetic tan but little extra melanin protection against sun damage, sun burn, or cancer.
⚪ UVB
Ultraviolet B (UVB) radiation is in the wavelength range 280 to 320 nm. Much of this band is blocked by the Earth's ozone layer, but some penetrates. UVB:
• triggers the formation of CPD-DNA damage (direct DNA damage), which in turn induces an increased melanin production.
• is more likely to cause a sunburn than UVA as a result of overexposure. The mechanism for sunburn and increased melanogenesis is identical.Both are caused by the direct DNA damage (formation of CPDs).
• produces Vitamin D in human skin.
• is reduced by virtually all sunscreens in accordance with their SPF.
• is thought to cause the formation of moles and some types of skin cancer.
• causes skin aging (but at a slower rate than UVA).
• stimulates the production of new melanin, which leads to an increase in the dark-colored pigment within a few days.
⚪ Mechanism of de-tanning action
De-tanning works by reducing the presence of melanin pigment in the skin. To accomplish this, there are several possible mechanisms of action:
• Inhibition of the activity of tyrosinase|Inhibition of the activity of tyrosinase: The catalytic action of tyrosinase is inhibited by the de-tanning agent.
• Inhibition of the expression or activation of tyrosinase: The anti melanogenic agent causes less tyrosinase to be generated or prevents tyrosinase from being activated to its functional form.
• Scavenging of the intermediate products of melanin synthesis.
• Preventing the transfer of melanosomes to keratinocytes
⚪ Inhibition of tyrosinase
Upregulation of tyrosinase caused by tyrosinase inhibitors. Several de-tanning agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis.
Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1, PMEL17, and many other important proteins involved in the function of melanocytes. Downregulation of MITF decreases melanogenesis and is a mechanism of action of some de-tanning agents. Various signaling pathways and genetic mutations influence the expression of MITF.
⚪ MC1R receptor and cAMP
The melanocortin 1 receptor (MC1R) is a transmembrane and G-protein coupled receptor expressed in melanocytes. MC1R is an important target for the regulation of melanogenesis. Agonism of MC1R increases the ratio of eumelanin to pheomelanin and increases the generation of melanin overall.
The MC1R and cAMP signaling pathway starts with the activation of MC1R, which causes activation of adenylyl cyclase (AC), which produces cyclic adenosine monophosphate (cAMP), which activates protein kinase A (PKA), which activates by protein phosphorylation cAMP response element-binding protein (CREB), which upregulates MITF, of which CREB is a transcription factor.
Alpha-melanocyte stimulating hormone (α-MSH), beta-melanocyte stimulating hormone (β-MSH), and adrenocorticotropic hormone are endogenous agonists of MC1R.[44]: 1175 Agouti signaling protein (ASIP) appears to be the only endogenous antagonist of MC1R. Synthetic MC1R agonists have been designed, such as the peptides afamelanotide and melanotan II.
⚪ Transfer of melanosomes
Within the skin, melanocytes are present in the basal layer of the epidermis; from these, melanocytes originate dendrites that reach keratinocytes.
Melanosomes, along with the melanin they contain, are transferred from melanocytes to keratinocytes when keratinocytes are low in the epidermis. Keratinocytes carry the melanosomes with them as they move toward the surface. Keratinocytes contribute to skin pigmentation by holding the melanin originating in melanocytes and inducing melanogenesis through chemical signals directed at melanocytes. The transfer of melanosomes to keratinocytes is a necessary condition for the visible pigmentation of the skin. Blocking this transfer is a mechanism of action of some de-tanning agents.
The protease-activated receptor 2 (PAR2) is a transmembrane and G-protein coupled receptor expressed in keratinocytes and involved in melanocyte transfer. Antagonists of PAR2 inhibit the transfer of melanosomes and have de-tanning effects, while agonists of PAR2 have the opposite effect.
GlowPotion™ Detan Face Mask
Share
Benefits
Benefits
⚜ Penetrates deep and remove the toughest of tan from the skin
⚜ Helps even out the skin tone and prevents the appearance of dark spots & pigmentation.
⚜ Treats tanning caused due to any reason like sun, pollution, etc.
⚜ Lightens existing blemishes, pigmentation and dark spots.
⚜ Heals acne and other scars
⚜ Repairs & rejuvenates dull skin by removing signs of fatigue from the face. Brightens the complexion, and combats dullness by reviving dull and tired skin
⚜ Reveals sensationally illuminating skin.
⚜ Removes the tanning from the skin without damaging the skin barrier
⚜ Enriched with antioxidants that protect cells from the damage caused by free radicals
⚜ Reduces Acne, White heads & Black heads
⚜ Tightens skin while making it supple and soft
⚜ Removes the dead tanned skin while deep cleansing the pores to reveal the healthy layer underneath
⚜ Helps in reproducing new cells, thus giving your skin a fresh and rejuvenated look
⚜ Repairs damage caused by sun and encourages even skin tone.
⚜ Stimulates collagen production and soothes and calms the skin
⚜ Locks in the necessary quantity of moisture, giving the facial skin the glow of youth
⚜ Smoothens skin texture and provides a relaxing and pampering spa experience at your own home
Fragrance
Fragrance
How to use
How to use
⚜ Cleanse your face and neck area with a cleanser
⚜ Gently pat dry with a soft towel
⚜ Take desired quantity of this powder, make a running paste by adding Moviestar™ toner or water
⚜ Apply on the face and neck area in a circular motion and leave for 10-15 minutes
⚜ The dried face pack should not be peeled or scratched
⚜ Rinse off with normal water with light scrubbing. Water should be sprayed on the face before removing the dried face pack.
⚜ After removing the mask, an ice cube should be rolled on the skin . This helps close open pores and tighten skin. It also tones and soothes the skin.
⚜ It should not be applied on eye contour area. The skin around the eyes is very delicate and requires a different approach as provided by Moviestar™ Eye Contour Cream.
When to use
When to use
⚜ Use it weekly, as a self beauty care regimen at home.
⚜ Ideal for year round usage as its all season formula provides complete rejuvenation and detoxification
Who should use
Who should use
⚜ All skin types
⚜ For women and men.
⚜ Ideal for weekly rejuvenation and detoxification
All Ingredients
All Ingredients
Powders of Jojoba, Rosehip, Lemon Peel, Kinnu Peel, Spearmint, Fuller's Earth, Guava Leaf and Essential Oils of Ylang Ylang & Mandarin.
Care Suggestions
Care Suggestions
⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to first usage.
Dermatologically Tested
Dermatologically Tested
This product has been thoroughly tested by dermatologists and is guaranteed safe and dermatologist approved.
Country of origin
Country of origin
Bharat
Scientific Explanation
Scientific Explanation
⚪ Tanning process
Melanin is a natural pigment produced by cells called melanocytes in a process called melanogenesis. Melanocytes produce two types of melanin: pheomelanin (red) and eumelanin (very dark brown). Melanin protects the body by absorbing ultraviolet radiation. Excessive UV radiation causes sunburn along with other direct and indirect DNA damage to the skin, and the body naturally combats and seeks to repair the damage and protect the skin by creating and releasing further melanin into the skin's cells. With the production of the melanin, the skin color darkens. The tanning process can be triggered by natural sunlight.
There are two different mechanisms involved in the production of a tan by UV exposure: Firstly, UVA radiation creates oxidative stress, which in turn oxidizes existing melanin and leads to rapid darkening of the melanin. UVA may also cause melanin to be redistributed (released from melanocytes where it is already stored), but its total quantity is unchanged. Skin darkening from UVA exposure does not lead to significantly increased production of melanin or protection against sunburn. In the second process, triggered primarily by UVB, there is an increase in production of melanin (melanogenesis), which is the body's reaction to direct DNA photodamage (formation of pyrimidine dimers) from UV radiation. Melanogenesis leads to delayed tanning, and typically becomes visible two or three days after exposure.The tan that is created by increased melanogenesis typically lasts for a few weeks or months, much longer than the tan that is caused by oxidation of existing melanin, and is also actually protective against UV skin damage and sunburn, rather than simply cosmetic. Typically, it can provide a modest Sun Protection Factor (SPF) of 3, meaning that tanned skin would tolerate up to 3 times the UV exposure as pale skin. However, in order to cause true melanogenesis-tanning by means of UV exposure, some direct DNA photodamage must first be produced, and this requires UVB exposure (as present in natural sunlight, or sunlamps that produce UVB). The ultraviolet frequencies responsible for tanning are often divided into the UVA and UVB ranges.
⚪ UVA
Ultraviolet A (UVA) radiation is in the wavelength range 320 to 400 nm. It is present more uniformly throughout the day, and throughout the year, than UVB. Most UVA is not blocked by the atmosphere's ozone layer. UVA causes the release of existing melanin from the melanocytes to combine with oxygen (oxidize) to create the actual tan color in the skin. UVA is blocked less than UVB by many sunscreens, but is blocked to some degree by clothing. UVA is known both to cause DNA damage and to be carcinogenic. However, it operates not by inducing direct DNA damage, but by producing reactive oxygen species which damage DNA indirectly. UVA induces a cosmetic tan but little extra melanin protection against sun damage, sun burn, or cancer.
⚪ UVB
Ultraviolet B (UVB) radiation is in the wavelength range 280 to 320 nm. Much of this band is blocked by the Earth's ozone layer, but some penetrates. UVB:
• triggers the formation of CPD-DNA damage (direct DNA damage), which in turn induces an increased melanin production.
• is more likely to cause a sunburn than UVA as a result of overexposure. The mechanism for sunburn and increased melanogenesis is identical.Both are caused by the direct DNA damage (formation of CPDs).
• produces Vitamin D in human skin.
• is reduced by virtually all sunscreens in accordance with their SPF.
• is thought to cause the formation of moles and some types of skin cancer.
• causes skin aging (but at a slower rate than UVA).
• stimulates the production of new melanin, which leads to an increase in the dark-colored pigment within a few days.
⚪ Mechanism of de-tanning action
De-tanning works by reducing the presence of melanin pigment in the skin. To accomplish this, there are several possible mechanisms of action:
• Inhibition of the activity of tyrosinase|Inhibition of the activity of tyrosinase: The catalytic action of tyrosinase is inhibited by the de-tanning agent.
• Inhibition of the expression or activation of tyrosinase: The anti melanogenic agent causes less tyrosinase to be generated or prevents tyrosinase from being activated to its functional form.
• Scavenging of the intermediate products of melanin synthesis.
• Preventing the transfer of melanosomes to keratinocytes
⚪ Inhibition of tyrosinase
Upregulation of tyrosinase caused by tyrosinase inhibitors. Several de-tanning agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis.
Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1, PMEL17, and many other important proteins involved in the function of melanocytes. Downregulation of MITF decreases melanogenesis and is a mechanism of action of some de-tanning agents. Various signaling pathways and genetic mutations influence the expression of MITF.
⚪ MC1R receptor and cAMP
The melanocortin 1 receptor (MC1R) is a transmembrane and G-protein coupled receptor expressed in melanocytes. MC1R is an important target for the regulation of melanogenesis. Agonism of MC1R increases the ratio of eumelanin to pheomelanin and increases the generation of melanin overall.
The MC1R and cAMP signaling pathway starts with the activation of MC1R, which causes activation of adenylyl cyclase (AC), which produces cyclic adenosine monophosphate (cAMP), which activates protein kinase A (PKA), which activates by protein phosphorylation cAMP response element-binding protein (CREB), which upregulates MITF, of which CREB is a transcription factor.
Alpha-melanocyte stimulating hormone (α-MSH), beta-melanocyte stimulating hormone (β-MSH), and adrenocorticotropic hormone are endogenous agonists of MC1R.[44]: 1175 Agouti signaling protein (ASIP) appears to be the only endogenous antagonist of MC1R. Synthetic MC1R agonists have been designed, such as the peptides afamelanotide and melanotan II.
⚪ Transfer of melanosomes
Within the skin, melanocytes are present in the basal layer of the epidermis; from these, melanocytes originate dendrites that reach keratinocytes.
Melanosomes, along with the melanin they contain, are transferred from melanocytes to keratinocytes when keratinocytes are low in the epidermis. Keratinocytes carry the melanosomes with them as they move toward the surface. Keratinocytes contribute to skin pigmentation by holding the melanin originating in melanocytes and inducing melanogenesis through chemical signals directed at melanocytes. The transfer of melanosomes to keratinocytes is a necessary condition for the visible pigmentation of the skin. Blocking this transfer is a mechanism of action of some de-tanning agents.
The protease-activated receptor 2 (PAR2) is a transmembrane and G-protein coupled receptor expressed in keratinocytes and involved in melanocyte transfer. Antagonists of PAR2 inhibit the transfer of melanosomes and have de-tanning effects, while agonists of PAR2 have the opposite effect.
DETAN FACE MASK
This is the ultimate facial glow DIY, a trademarked innovation created from organic herbs containing essential bioactive compounds and phytochemicals which penetrate deep and remove the toughest of tan from the skin without damaging the skin barrier, and even out the skin tone by reducing the appearance of dark spots & pigmentation. This 100% natural and preservative-free anti-pollution face mask helps heal acne scars and other blemishes, and helps repair & rejuvenate dull skin by removing signs of fatigue from the face, thus revealing sensationally illuminating skin.
⚜
Powered by the revolutionary 3-in-1 GlowPotion™ formula for stunning radiance and mesmerizing complexion, it stimulates collagen production and helps produce new cells, thus giving your skin a fresh and rejuvenated look. Enriched with antioxidants that protect cells from the damage caused by free radicals, it also repairs existing damage caused by sun. This unique herbal product smoothens skin texture and provides a relaxing and pampering spa experience at your own home. This once a week self care routine would provide drastic before and after effect on your complexion, skin glow, and texture. A complete spa for your facial skin.
Parlour VS self care regimen
Be in control of what is being applied to your face, unlike a spa or a parlour where you are at the mercy of the staff. Most spas and parlours use products of brands from which they earn commission. The product being applied on your face isn’t necessarily the best for your skin but it’s definitely the best for the profit margin of the establishment.A recent year long scientific study has revealed that majority of users develop skin lesions within 2.3 weeks of the parlour procedure. Acneiform eruptions (25.4% of the users), or exacerbation of existing acne (15.7% of the users) were the most common presenting dermatoses, followed by folliculitis and hyperpigmentation of face.
⚜
Your facial skin is precious beyond any treasure; please treat it with care. Nourish your skin with the safest and the best. A once a week self care regimen with GlowPotion™ Face Mask is better than any spa treatment. That’s the BestIndian™ guarantee !
REJUVENATION | DETOX | EXFOLIATION
100% Natural | 100% Preservative Free
Organic | Paraben & Sulfates Free | Herbal
Lightens Scars & Complexion
Color: | - |
---|---|
Size: | - |
Material: | - |
Dimensions: | - |
25% of Profits for Social Welfare
BESTINDIAN™ SETS ASIDE 25% OF ALL ANNUAL PROFITS FOR SOCIAL WELFARE
Exceedingly high amount of money is spent on advertising and publicity by the world’s Beautycare and Perfumes brands for the promotion of their products. The United States is the largest advertising market in the world, with ad spending amounting to 250 billion U.S. dollars in 2020. Advertising expenditure (AdEx) in India is expected to grow 15.5% to reach ₹1,46,450 crore in 2023. By 2024, India is projected to spend $14.8 billion.
On an average, companies spend 15% - 25% of their annual revenue for their marketing budget. The amount of capital and resources that almost all companies and businesses spend every year on hiring celebrities as brand ambassadors for advertising their products, can launch help numerous interplanetary space missions by ISRO, help protect environment by reforestation, and provide jobs for millions.
Imagine a world where, instead of competing with each other on the basis of how much they spend for their respective advertising, the companies competed on how much they have spent for social welfare and for the betterment of the earth. This is the kind of world that BestIndian™ is creating!
25% OF PROFITS FROM THE SALE OF EVERY PRODUCT BOUGHT BY YOU WOULD BE UTILIZED FOR THE FOLLOWING CAUSES:
(1) To provide employment to Indian youth by setting up Studios for animation & filmmaking in India:
Digital Content in general, and animation in particular have immense potential for generating employment. BestIndian™ plans on starting animation and film studios in smaller towns, particularly in the neglected regions of India. Youth from the hinterland should be provided equal career opportunities and awareness as those from the metropolitan cities, to help prevent migration.
(2) To set up animal rescue shelters for the helpless stray and abandoned animals including cows, dogs, mules etc:
India had always been known for the beautiful and harmonious coexistence between humans and numerous animal species. However, in recent times there has been a rapid rise in human-animal conflicts. Helpless stray and abandoned animals need to be treated with empathy, and at the same time safety of vulnerable humans including children and the elderly needs to be taken into account. BestIndian™ plans to set up animal rescue, welfare and rehabilitation centres, in all those Indian towns which lack this facility.
(3) To create more urban forests in India by planting native Indian fruit and Ayurvedic trees.
Rapid and often unplanned urbanization has resulted in an India urban scape which is devoid of greenery. Unless cities include development of nature in their development plans, Indian cities would continue suffering intense heat waves, dust storms, unbreathable winter air, smog, etc. BestIndian™ has created #AtalVatika, an urban forest In Dehradun, by planting numerous native Indian trees, and plans to create numerous more such Vatikas in as many cities and towns as possible.
BestIndian™ is a medium for change and believes in all round development of all sections of the society, protection of nature, conservation of wildlife, and empathy for animals. BestIndian™ doesn’t believe in advertising on television or in buying followers on social media, and refuses to hire the services of Celebrities, Actors, or cricketers as the BestIndian™ brand ambassadors. BestIndian™ doesn’t send out free sample products to get favourable reviews by influencers.
BestIndian™ has made a name for itself on its inherent merits, and has earned its goodwill and reputation due to the quality of its products and user satisfaction, instead of resorting to artificial brand building by paid promotion of the brand.
Companies compete on the lines of “Our company’s Brand Ambassador celebrity is bigger than our competitor’s”, or “We have more social media followers than our competitor”, etc. BestIndian™ requests companies to compete on the basis of the amount spent by them on social welfare.
Star Ingredients
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Lemon
Citrus limon's phytochemicals are citral, carveol, carvone, citronellol, and citronellal, Linalool and linalyl acetate, pinene, alpha-hydroxy acid etc., which organically exfoliate the upper layer of the skin, remove the tan, moisturize the skin and keep it hydrated.
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Rosehip
Rosehip's bioactive compounds include flavonoids, tannins, anthocyanin, phenolic compounds, fatty oil, organic acids, etc. Rosehip contains carotenoids, which help treat early signs of aging like fine lines, wrinkles, blemishes, acne scars, etc., by creating new skin cells.
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Mandarin
Mandarin is utilized by dermatologists for acne-prone skin, as it is packed with Vitamins and antioxidants which help to rebalance the skin for a clearer, cleaner appearance. Narirutin and hesperidin are the major flavanone compounds in mandarin.
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