⚪ 24 Hour Natural Shine & Smoothness
⚪ Ultimate Styling+Protection+Nourishment
⚪ All-In-1 Haircare
⚪ Leave-on formula

⚜ Hair-fall control –
This oil’s ingredient Fenugreek seeds are respected as an antiandrogen of plant origin. Diosgenin in fenugreek has been shown to have oestrogenic activity which leads to inhibition of dihydrotestosterone. Flavonoids have also been shown to have anti-inflammatory and anti-proliferative effect. Aditionally, Flavonoids and Trigonelline cause vasodilation in the scalp. These factors contribute in greatly controlling Androgenetic alopecia.
⚜ Nourishes Hair growth –
As the oil has enhanced penetration and reaches up to the hair follicle, it increases the circulation of the scalp, thereby increasing hair growth
⚜ Antioxidant effect –
It is resistant to oxidative deterioration because of the presence of endogenous antioxidants .
⚜ Anti-dandruff, anti- frizz, anti-dryness, anti-split ends(Moisturizing agent)–
It moisturizes the hair follicle and prevents dryness. It has enhanced penetration capacity which prevents split-ends and frizz.
⚜ Fortifies coloured hair––
Colouring take s a toll on the hair. This unique oil provides the much needed nourishment to coloured hair and fortifies them against any more damage in the future.
⚜ Antibacterial activity –
one of its ingredient phytochemicals is a monoglyceride called Monolaurin which shows its efficacy as an antibacterial agent. It acts by disintegrating the lipid membrane of different bacteria such as Propionibacterium acne, Staphylococcus aureus, Staphylococcus epidermidi. It Exhibits bactericidal activity against Pseudomonas aeruginosa, Escherichia coli, Proteus vulgaris, and Bacillus subtilis
⚜ Antifungal activity –
It has fungicidal effect against Trichoderma viride, Aspergillus niger, Aspergillus oryzae and Aspergillus flavus. It also has effect against harmful pathogenic fungi - Fusarium graminearu. Monolaurin also exhibits antifungal activity.
⚜ Anti-inflammatory properties –
The lignans present in this oil have anti-inflammatory properties
⚜ Emollients –
It has emollient property, hence it is used to soften and moisturize dry hair. BestIndian™ Ultimate Styling Rejuvenator Oil forms a coating over the hair shaft, thereby sealing the cuticle and trapping the moisture inside. Its ingredient phytochemical lecithin, which is provide by Fenugreek, is a natural emollient and helps in strengthening and moisturization of hair
⚜ Elasticity –
It increases the elasticity of the hair as it fills the gap between cuticle cells
⚜ Graying of hair –
Graying of hair is mediated through ROS leading to damage of the melanocytes, thereby leading to decreased pigmentation. BestIndian™ Ultimate Styling Rejuvenator Oil, because of the presence of Vitamin C, gallic acid, ellagic acid, and tannins can absorb ROS and prevent premature graying.
⚜ Detangling Lubricant –
It provides increased slip in between the hair strands, detangles the hair, smoothens and flattens the cuticle surface which improves the health and appearance of the strands
⚜ Preventing protein loss –
Due to its low molecular weight and straight linear chain it is able to penetrate inside the hair shaft thereby, preventing loss of protein from the hair.
⚜ Environmental shield against hair damage –
This oil has fatty acids that are rich in double bonds and hence protect against UV radiation induced structural damage. Tocopherol + tocotrienol + sesamin extract significantly reduced the UV-induced damage. It forms a protective coat around the hair, thereby preventing hair damage due to various environmental triggers including pollution, dust, etc.
⚜ Diffusion barrier –
Surface oil films and penetrated oil molecules form a diffusion barrier. Role of fiber swelling on restrictive narrowing of the cell membrane complexes (CMCs), which form the diffusion pathways in the hair fiber is well established, as oil film is the main resistance to moisture diffusion. The lowering of the diffusion coefficient of water vapor by oil films will slow the loss of moisture, an effect similar to "moisturization" of hair.

Tea tree ⚜ Rosemary ⚜ Parijat

⚜ Invigoratingly unique fragrance of the Ultimate HairStyling Rejuvenator Oil by BestIndian™ transports you to a freshening walk in the pristine forests of the Himalayas.
⚜ The green top notes, floral middle notes and woody base notes of the exotic Parijat (Nyctanthes Arbor-tristis) combine with Rosemary's freshly woody-herbaceous aroma, and Tea tree's strong mint nuances to provide an unforgettable fragrance which is soaked by the hair fiber and released subtly throughout the day.
⚜ This unique fragrance is 100% natural as it has been created from unique combinations of organic herbs and botanical extracts, and is guaranteed free of any synthetic chemical or paraben.

⚪ As a Rejuvenator:

Specially formulated to be used as an intensive repair and rejuvenation treatment, often called oiling your hair, which provides intense nourishment to dry or damaged hair and the scalp, encouraging healthier hair growth.
Oiling your hair involves applying a generous amount of hair oil to your hair and scalp, massaging it into the scalp, and leaving the oil in for a few hours or overnight. This strengthens the hair from the inside out and provides intensive nourishment.

⚜ Step One: Applying the Oil:
Start by sectioning your hair and applying the oil to your scalp, working it all the way down to the ends. Use your fingertips to massage the oil into your scalp, which helps to improve blood circulation, promoting scalp health and healthy hair growth. You can use a wide-tooth comb to distribute the hair oil evenly throughout your hair.
⚜ Step Two: Let the skin absorb the oil:
Leave the oil on your hair for at least an hour or overnight for a more intensive treatment. You can cover your hair with a shower cap or towel to help the oil penetrate your hair better and protect your pillowcase while you sleep.
⚜ Step Three: Wash and Condition
To wash out the oil, shampoo with a gentle shampoo, preferably BestIndian™ Ultimate Conditioning Shampoo which keeps the hair moisturized.
⚜ How Often Should You Oil Your Hair?
This depends on your hair type, damage level and needs. Oiling the hair once or twice a week is advised. Dry or damaged hair types should apply this intensive treatment more often.

⚪ As a Styling Accessory:

⚜ This unique product can be used as a hair styler in itself as it provides frizz free, silky hair which is apt for the naturally shiny look.
⚜ For a slicked back look, apply on the roots, mid-lengths, and to the ends of your hair. Massage the oil in the scalp with your fingertips for a uniform distribution.
⚜ For all other hairstyles, apply from the mid-lengths to the ends of your hair (avoid root application to prevent weighed down appearance of the hair and to provide volume to the hairstyle).

⚜ As a Pre-Shampoo Treatment:
Applying hair oil before shampooing helps nourish and strengthen the hair while protecting it from moisture loss during the shampooing process, especially when the shampoo is not organic. To use hair oil as a pre-shampoo treatment, apply the oil from the mid-lengths to the ends of the hair; leave it on from 5 to 10 minutes, then shampoo, condition, and style as desired.
⚜ As a Pre-Blowdry Treatment:
Using this hair oil before blow drying helps boost smoothness, prevent frizz, and increase shine. Apply the hair oil from the mid-lengths to the ends of your damp, freshly washed hair. Blow-dry the hair as usual, using a round brush for added smoothness and lift at the roots.
⚜ As a Styling Routine
Apply this hair oil while the hair is damp to protect the hair fiber from unwanted frizz as it dries into a subtly shiny version of its natural texture.
⚜ Frizz and Flyaways prevention:
Hair oil is most commonly used as the last step in your styling routine to add moisture, shine, and eliminate frizz. Simply apply a small amount of this hair oil to the hair after styling, focusing on the ends and any other areas that tend to frizz. You can also use a tiny drop to smooth down any stray flyaways.
⚜ Refresh the hairstyle Between Wash Days
If you’re trying to extend the time between washes, hair oil can be a great way to freshen up your style and add moisture. Applying a drop or two to your hair, focusing on the mid-lengths and ends, will help to revive your hair and add shine.

⚪ For intensive rejuvenation and nourishment:
Apply before going to bed. The frequency of usage would depend on your hair type, damage level and needs. Oiling the hair once or twice a week is advised. Dry or damaged hair types should apply this intensive treatment more often.

⚪ For styling :
Any time of the day or night for providing lustrous sheen and smoothness. On wet hair, you can lock in precious moisture by applying a few drops along the lengths and ends, making sure you distribute evenly, before drying. On already-dry hair, hair oil can help smooth down any frizz or flyaways, and is particularly good for adding shine to curls and waves.
⚜ Pre-Shampoo Treatment:
To use hair oil as a pre-shampoo treatment, apply the oil and leave it on from 5 to 10 minutes, before shampooing.
⚜ Pre-Blowdry Treatment

⚪ BestIndian Ultimate Hair Styling Oil is for everyone who ...

⚜ is facing increasing hair-fall
⚜ has brittle hair that break easily
⚜ steps out in the sun and needs protection from UV damage
⚜ has hair with dry texture
⚜ has dull looking hair
⚜ wants to prevent split-ends
⚜ wants to control frizz
⚜ wants to conquer dandruff
⚜ wants an environmental shield for hair
⚜ has hair that tangles easily
⚜ uses hair-styling tools such as straighteners, curlers, etc
⚜ steps out in the sun
⚜ encounters dusty outdoors
⚜ is mostly indoors in dry air-conditioned environment like workplace, etc.
⚜ colors his/her hair
⚜ uses styling products on their hair
⚜ whose hair are graying prematurely
⚜ whose hair growth is slow
⚜ whose hair is rough and non lubricated

BestIndian™ practices 100% transparency, and believes in disclosing all ingredients used in its products. BestIndian™ guarantees that no other ingredient, apart from those listed below, has been used in this natural and synthetic chemicals free BestIndian™ Luxury:

Almond oil ⚜ Sesame oil ⚜ Methi oil ⚜ Coconut oil ⚜ Bakuchi oil ⚜ Essential oils of Rosemary, Tea tree & Parijat ⚜ Visibly floating herbs.

⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to the first usage.
⚜ Best before 24 months from manufacturing.

This product has been thoroughly tested by dermatologists and is guaranteed safe and dermatologist approved.

Bharat

The hair follicle is a “complex miniorgan” that produces hair shafts from terminally differentiated keratinocytes. In association with the sebaceous gland, apocrine gland and arrector pili muscle (APM), the hair follicle forms the pilosebaceous unit. Eccrine glands have also recently been shown to be integrated within the pilosebaceous unit. Scalp hair follicles cluster to form compound pilosebaceous units, consisting of one primary follicle and one or more secondary follicles associated with a single APM and single sebaceous gland. All the hairs from a follicular unit emerge through a shared infundibulum
On average, a human has between 2 and 5 million hair follicles, of which 100,000 are on the scalp. The hair follicle is a complex structure that integrates tissues that arise embryologically from ectoderm, neuroectoderm and mesoderm. Epidermal and mesenchymal cells integrate, proliferate, differentiate and cycle through phases of the hair cycle called anagen, catagen and telogen. The hair fibre forms and elongates during anagen, is retained during catagen and early telogen and then is shed mid-telogen at a point in time called exogen. The late-telogen period after exogen and before the onset of the next anagen, where the follicle is empty, is called kenogen. As the rate of linear hair growth remains relatively constant throughout life, the main determinant of hair length is anagen duration. Kenogen duration has an impact on hair density but not length.
Intricate pathways regulate hair cycling and anagen duration and determine hair growth. Over the last few years, progress in molecular biology and genetics, as well as the development of new experimental approaches, has brought together scientists from all fields working together to crate the ultimate formula for the rejuvenation and protection of hair follicles. Developmental biologists, geneticists, endocrinologists, and dermatologists thoroughly studied and researched the many diverse facets of hair follicle biology including neuroectodermal– mesenchymal interactions, immunology, pigmentation, and stem cell biology.
These scientists determined the herb-ingredient-target protein networks and ingredient-associated protein (gene)-associated pathway networks and calculated the weighted degree centrality to define the strength of the connections, and created the100% natural and herbal BestIndian™ Ultimate Hair Styling Rejuvenator Oil.
Data shows that the ingredient vital medicinal herbs of BestIndian™ Ultimate Hair Styling Rejuvenator Oil exert therapeutic effects on premature hair loss, mainly mediated via regulation of various target genes and proteins, including acetylcholinesterase (AChE), phospholipase A2 (PLA2) subtypes, ecto-5-nucleotidase (NTE5), folate receptor (FR), nicotinamide N-methyltransferase (NNMT), and quinolinate phosphoribosyltransferase (QPRT). Findings regarding target genes/proteins and pathways of medicinal herbs associated with prevention of premature hair loss, provide understanding of the pathogenesis and therapeutic mechanism of medicinal herbs for preventing premature hair loss and reduction in density.
Analysis of hair has revealed a composition of iron, oxygen, hydrogen, nitrogen and sulphur. Thus, an adequate supply of blood containing these minerals is essential for hair growth during anagen. Anagen is associated with a rearrangement of skin vasculature, an increase in skin perfusion, and angiogenesis. Various vitamins and minerals are responsible for the modulation of angiogenesis during anagen and therefore are important. In addition, multiple vitamins, minerals, and herbal phytochemicals and bioactive compounds stimulate hair growth or prevent hair loss by various mechanisms, and thus deficiencies in these can cause hair loss.
Phytochemicals have beneficial effects on hair health. The underlying mechanisms associated with hair growth-promoting properties of the phytochemicals are utilised in the formula of BestIndian™ Ultimate Hair Styling Rejuvenator Oil. The results show that hair growth-promoting properties of phytochemicals are associated with the TGF-β pathway, β-catenin, JAK/STAT3 pathway, ERK signaling pathway, and 5α-reductase inhibitory property. Some studies proposed that phytochemicals are more effective than conventional hair loss regimens such as minoxidil and finasteride.

BestIndian™ Ultimate Hair Styling Rejuvenator Oil contains phytochemicals and bioactive compounds including Vitamins, minerals that stimulate hair growth or prevent hair loss by various mechanisms.

Agents improving blood supply to the scalp include:
Niacin (vitamin B3)
Vitamin B complex
Ascorbic acid (vitamin C)
Tocopherol (vitamin E)
Sesame Oil
Rosemary oil
Methi (Fenugreek)
Tea tree oil
Almond oil

Cofactors for carboxylases that catalyse an essential step in intermediate metabolism:
Biotin
Antioxidants:
Zinc, Bakuchi oil

Agents that inhibit or reduce 5 alpha reductase activity:
Inhibitors: Parijat, ginkgo biloba, etc.

⚪ 24 Hour Natural Shine & Smoothness
⚪ Ultimate Styling+Protection+Nourishment
⚪ All-In-1 Haircare
⚪ Leave-on formula

⚜ Hair-fall control –
This oil’s ingredient Fenugreek seeds are respected as an antiandrogen of plant origin. Diosgenin in fenugreek has been shown to have oestrogenic activity which leads to inhibition of dihydrotestosterone. Flavonoids have also been shown to have anti-inflammatory and anti-proliferative effect. Aditionally, Flavonoids and Trigonelline cause vasodilation in the scalp. These factors contribute in greatly controlling Androgenetic alopecia.
⚜ Nourishes Hair growth –
As the oil has enhanced penetration and reaches up to the hair follicle, it increases the circulation of the scalp, thereby increasing hair growth
⚜ Antioxidant effect –
It is resistant to oxidative deterioration because of the presence of endogenous antioxidants .
⚜ Anti-dandruff, anti- frizz, anti-dryness, anti-split ends(Moisturizing agent)–
It moisturizes the hair follicle and prevents dryness. It has enhanced penetration capacity which prevents split-ends and frizz.
⚜ Fortifies coloured hair––
Colouring take s a toll on the hair. This unique oil provides the much needed nourishment to coloured hair and fortifies them against any more damage in the future.
⚜ Antibacterial activity –
one of its ingredient phytochemicals is a monoglyceride called Monolaurin which shows its efficacy as an antibacterial agent. It acts by disintegrating the lipid membrane of different bacteria such as Propionibacterium acne, Staphylococcus aureus, Staphylococcus epidermidi. It Exhibits bactericidal activity against Pseudomonas aeruginosa, Escherichia coli, Proteus vulgaris, and Bacillus subtilis
⚜ Antifungal activity –
It has fungicidal effect against Trichoderma viride, Aspergillus niger, Aspergillus oryzae and Aspergillus flavus. It also has effect against harmful pathogenic fungi - Fusarium graminearu. Monolaurin also exhibits antifungal activity.
⚜ Anti-inflammatory properties –
The lignans present in this oil have anti-inflammatory properties
⚜ Emollients –
It has emollient property, hence it is used to soften and moisturize dry hair. BestIndian™ Ultimate Styling Rejuvenator Oil forms a coating over the hair shaft, thereby sealing the cuticle and trapping the moisture inside. Its ingredient phytochemical lecithin, which is provide by Fenugreek, is a natural emollient and helps in strengthening and moisturization of hair
⚜ Elasticity –
It increases the elasticity of the hair as it fills the gap between cuticle cells
⚜ Graying of hair –
Graying of hair is mediated through ROS leading to damage of the melanocytes, thereby leading to decreased pigmentation. BestIndian™ Ultimate Styling Rejuvenator Oil, because of the presence of Vitamin C, gallic acid, ellagic acid, and tannins can absorb ROS and prevent premature graying.
⚜ Detangling Lubricant –
It provides increased slip in between the hair strands, detangles the hair, smoothens and flattens the cuticle surface which improves the health and appearance of the strands
⚜ Preventing protein loss –
Due to its low molecular weight and straight linear chain it is able to penetrate inside the hair shaft thereby, preventing loss of protein from the hair.
⚜ Environmental shield against hair damage –
This oil has fatty acids that are rich in double bonds and hence protect against UV radiation induced structural damage. Tocopherol + tocotrienol + sesamin extract significantly reduced the UV-induced damage. It forms a protective coat around the hair, thereby preventing hair damage due to various environmental triggers including pollution, dust, etc.
⚜ Diffusion barrier –
Surface oil films and penetrated oil molecules form a diffusion barrier. Role of fiber swelling on restrictive narrowing of the cell membrane complexes (CMCs), which form the diffusion pathways in the hair fiber is well established, as oil film is the main resistance to moisture diffusion. The lowering of the diffusion coefficient of water vapor by oil films will slow the loss of moisture, an effect similar to "moisturization" of hair.

Tea tree ⚜ Rosemary ⚜ Parijat

⚜ Invigoratingly unique fragrance of the Ultimate HairStyling Rejuvenator Oil by BestIndian™ transports you to a freshening walk in the pristine forests of the Himalayas.
⚜ The green top notes, floral middle notes and woody base notes of the exotic Parijat (Nyctanthes Arbor-tristis) combine with Rosemary's freshly woody-herbaceous aroma, and Tea tree's strong mint nuances to provide an unforgettable fragrance which is soaked by the hair fiber and released subtly throughout the day.
⚜ This unique fragrance is 100% natural as it has been created from unique combinations of organic herbs and botanical extracts, and is guaranteed free of any synthetic chemical or paraben.

⚪ As a Rejuvenator:

Specially formulated to be used as an intensive repair and rejuvenation treatment, often called oiling your hair, which provides intense nourishment to dry or damaged hair and the scalp, encouraging healthier hair growth.
Oiling your hair involves applying a generous amount of hair oil to your hair and scalp, massaging it into the scalp, and leaving the oil in for a few hours or overnight. This strengthens the hair from the inside out and provides intensive nourishment.

⚜ Step One: Applying the Oil:
Start by sectioning your hair and applying the oil to your scalp, working it all the way down to the ends. Use your fingertips to massage the oil into your scalp, which helps to improve blood circulation, promoting scalp health and healthy hair growth. You can use a wide-tooth comb to distribute the hair oil evenly throughout your hair.
⚜ Step Two: Let the skin absorb the oil:
Leave the oil on your hair for at least an hour or overnight for a more intensive treatment. You can cover your hair with a shower cap or towel to help the oil penetrate your hair better and protect your pillowcase while you sleep.
⚜ Step Three: Wash and Condition
To wash out the oil, shampoo with a gentle shampoo, preferably BestIndian™ Ultimate Conditioning Shampoo which keeps the hair moisturized.
⚜ How Often Should You Oil Your Hair?
This depends on your hair type, damage level and needs. Oiling the hair once or twice a week is advised. Dry or damaged hair types should apply this intensive treatment more often.

⚪ As a Styling Accessory:

⚜ This unique product can be used as a hair styler in itself as it provides frizz free, silky hair which is apt for the naturally shiny look.
⚜ For a slicked back look, apply on the roots, mid-lengths, and to the ends of your hair. Massage the oil in the scalp with your fingertips for a uniform distribution.
⚜ For all other hairstyles, apply from the mid-lengths to the ends of your hair (avoid root application to prevent weighed down appearance of the hair and to provide volume to the hairstyle).

⚜ As a Pre-Shampoo Treatment:
Applying hair oil before shampooing helps nourish and strengthen the hair while protecting it from moisture loss during the shampooing process, especially when the shampoo is not organic. To use hair oil as a pre-shampoo treatment, apply the oil from the mid-lengths to the ends of the hair; leave it on from 5 to 10 minutes, then shampoo, condition, and style as desired.
⚜ As a Pre-Blowdry Treatment:
Using this hair oil before blow drying helps boost smoothness, prevent frizz, and increase shine. Apply the hair oil from the mid-lengths to the ends of your damp, freshly washed hair. Blow-dry the hair as usual, using a round brush for added smoothness and lift at the roots.
⚜ As a Styling Routine
Apply this hair oil while the hair is damp to protect the hair fiber from unwanted frizz as it dries into a subtly shiny version of its natural texture.
⚜ Frizz and Flyaways prevention:
Hair oil is most commonly used as the last step in your styling routine to add moisture, shine, and eliminate frizz. Simply apply a small amount of this hair oil to the hair after styling, focusing on the ends and any other areas that tend to frizz. You can also use a tiny drop to smooth down any stray flyaways.
⚜ Refresh the hairstyle Between Wash Days
If you’re trying to extend the time between washes, hair oil can be a great way to freshen up your style and add moisture. Applying a drop or two to your hair, focusing on the mid-lengths and ends, will help to revive your hair and add shine.

⚪ For intensive rejuvenation and nourishment:
Apply before going to bed. The frequency of usage would depend on your hair type, damage level and needs. Oiling the hair once or twice a week is advised. Dry or damaged hair types should apply this intensive treatment more often.

⚪ For styling :
Any time of the day or night for providing lustrous sheen and smoothness. On wet hair, you can lock in precious moisture by applying a few drops along the lengths and ends, making sure you distribute evenly, before drying. On already-dry hair, hair oil can help smooth down any frizz or flyaways, and is particularly good for adding shine to curls and waves.
⚜ Pre-Shampoo Treatment:
To use hair oil as a pre-shampoo treatment, apply the oil and leave it on from 5 to 10 minutes, before shampooing.
⚜ Pre-Blowdry Treatment

⚪ BestIndian Ultimate Hair Styling Oil is for everyone who ...

⚜ is facing increasing hair-fall
⚜ has brittle hair that break easily
⚜ steps out in the sun and needs protection from UV damage
⚜ has hair with dry texture
⚜ has dull looking hair
⚜ wants to prevent split-ends
⚜ wants to control frizz
⚜ wants to conquer dandruff
⚜ wants an environmental shield for hair
⚜ has hair that tangles easily
⚜ uses hair-styling tools such as straighteners, curlers, etc
⚜ steps out in the sun
⚜ encounters dusty outdoors
⚜ is mostly indoors in dry air-conditioned environment like workplace, etc.
⚜ colors his/her hair
⚜ uses styling products on their hair
⚜ whose hair are graying prematurely
⚜ whose hair growth is slow
⚜ whose hair is rough and non lubricated

BestIndian™ practices 100% transparency, and believes in disclosing all ingredients used in its products. BestIndian™ guarantees that no other ingredient, apart from those listed below, has been used in this natural and synthetic chemicals free BestIndian™ Luxury:

Almond oil ⚜ Sesame oil ⚜ Methi oil ⚜ Coconut oil ⚜ Bakuchi oil ⚜ Essential oils of Rosemary, Tea tree & Parijat ⚜ Visibly floating herbs.

⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to the first usage.
⚜ Best before 24 months from manufacturing.

This product has been thoroughly tested by dermatologists and is guaranteed safe and dermatologist approved.

Bharat

The hair follicle is a “complex miniorgan” that produces hair shafts from terminally differentiated keratinocytes. In association with the sebaceous gland, apocrine gland and arrector pili muscle (APM), the hair follicle forms the pilosebaceous unit. Eccrine glands have also recently been shown to be integrated within the pilosebaceous unit. Scalp hair follicles cluster to form compound pilosebaceous units, consisting of one primary follicle and one or more secondary follicles associated with a single APM and single sebaceous gland. All the hairs from a follicular unit emerge through a shared infundibulum
On average, a human has between 2 and 5 million hair follicles, of which 100,000 are on the scalp. The hair follicle is a complex structure that integrates tissues that arise embryologically from ectoderm, neuroectoderm and mesoderm. Epidermal and mesenchymal cells integrate, proliferate, differentiate and cycle through phases of the hair cycle called anagen, catagen and telogen. The hair fibre forms and elongates during anagen, is retained during catagen and early telogen and then is shed mid-telogen at a point in time called exogen. The late-telogen period after exogen and before the onset of the next anagen, where the follicle is empty, is called kenogen. As the rate of linear hair growth remains relatively constant throughout life, the main determinant of hair length is anagen duration. Kenogen duration has an impact on hair density but not length.
Intricate pathways regulate hair cycling and anagen duration and determine hair growth. Over the last few years, progress in molecular biology and genetics, as well as the development of new experimental approaches, has brought together scientists from all fields working together to crate the ultimate formula for the rejuvenation and protection of hair follicles. Developmental biologists, geneticists, endocrinologists, and dermatologists thoroughly studied and researched the many diverse facets of hair follicle biology including neuroectodermal– mesenchymal interactions, immunology, pigmentation, and stem cell biology.
These scientists determined the herb-ingredient-target protein networks and ingredient-associated protein (gene)-associated pathway networks and calculated the weighted degree centrality to define the strength of the connections, and created the100% natural and herbal BestIndian™ Ultimate Hair Styling Rejuvenator Oil.
Data shows that the ingredient vital medicinal herbs of BestIndian™ Ultimate Hair Styling Rejuvenator Oil exert therapeutic effects on premature hair loss, mainly mediated via regulation of various target genes and proteins, including acetylcholinesterase (AChE), phospholipase A2 (PLA2) subtypes, ecto-5-nucleotidase (NTE5), folate receptor (FR), nicotinamide N-methyltransferase (NNMT), and quinolinate phosphoribosyltransferase (QPRT). Findings regarding target genes/proteins and pathways of medicinal herbs associated with prevention of premature hair loss, provide understanding of the pathogenesis and therapeutic mechanism of medicinal herbs for preventing premature hair loss and reduction in density.
Analysis of hair has revealed a composition of iron, oxygen, hydrogen, nitrogen and sulphur. Thus, an adequate supply of blood containing these minerals is essential for hair growth during anagen. Anagen is associated with a rearrangement of skin vasculature, an increase in skin perfusion, and angiogenesis. Various vitamins and minerals are responsible for the modulation of angiogenesis during anagen and therefore are important. In addition, multiple vitamins, minerals, and herbal phytochemicals and bioactive compounds stimulate hair growth or prevent hair loss by various mechanisms, and thus deficiencies in these can cause hair loss.
Phytochemicals have beneficial effects on hair health. The underlying mechanisms associated with hair growth-promoting properties of the phytochemicals are utilised in the formula of BestIndian™ Ultimate Hair Styling Rejuvenator Oil. The results show that hair growth-promoting properties of phytochemicals are associated with the TGF-β pathway, β-catenin, JAK/STAT3 pathway, ERK signaling pathway, and 5α-reductase inhibitory property. Some studies proposed that phytochemicals are more effective than conventional hair loss regimens such as minoxidil and finasteride.

BestIndian™ Ultimate Hair Styling Rejuvenator Oil contains phytochemicals and bioactive compounds including Vitamins, minerals that stimulate hair growth or prevent hair loss by various mechanisms.

Agents improving blood supply to the scalp include:
Niacin (vitamin B3)
Vitamin B complex
Ascorbic acid (vitamin C)
Tocopherol (vitamin E)
Sesame Oil
Rosemary oil
Methi (Fenugreek)
Tea tree oil
Almond oil

Cofactors for carboxylases that catalyse an essential step in intermediate metabolism:
Biotin
Antioxidants:
Zinc, Bakuchi oil

Agents that inhibit or reduce 5 alpha reductase activity:
Inhibitors: Parijat, ginkgo biloba, etc.