⚪ Provides a total solution for all challenges of signs of aging and loss of skin's elasticity, etc.
⚪ Collagen Boost: Stimulates collagen producing receptors in the skin to greatly boost the production of collagen to roll back years and regain youthful skin
⚪ Prevention: Prevents the appearance of wrinkles, fine lines, dark spots, pigmentation etc. by intensive skin care
⚪ Rejuvenation: Rejuvenates the skin overnight by providing intensive care and complete nourishment
⚪ Restoration: Restores the elasticity of the skin
⚪ Reduction in photo damage without the risks involved with usage of Retinoids
⚪ Stimulates the cellular activity and strengthens the protective barriers of the skin to avoid loss of moisture and collagen promoting tissues
⚪ Reduction of inflammation of Acne skin: Prevents acne flare-ups and breakouts. It balances skin's sebum production to reduce the shine, which can prevent breakouts and acne
⚪ Stimulates fibroblasts and cause an increase in collagen synthesis
⚪ Skin Tone & Brightening: Improves the skin's tone and texture
⚪ Anti-oxidant properties: Protects squalene and many skin lipids from oxidation due to its excellent antioxidant activity
⚪ Prevents dysregulation in melanin synthesis which results in hyper pigmentary disorders, including melasma, freckles, age spots, solar lentigo, etc
⚪ Solves hyperpigmentation and sun damage.
⚪ Improves the skin's hydration levels
⚪ Increases skin firmness and brings a reduction in redness, and an overall improvement in skin condition
⚪ Increases cell turnover
⚪ Herbal ⚜ Ayurvedic ⚜ Natural ⚜ Organic
⚪ 100 % FDA compliant

⚪ ElixirOfYouth™ facial serum has a mesmerizing fragrance provided by the unique symphony of Frankincense, Vetiver, and Palmarosa.
⚜ Palmarosa’s fragrance is citrusy herbaceous and metallically sweet with hints of rose.
⚜ Vetiver’s scent is earthy and woody with notes of freshly cut grass and blended citrus on a warm day, with damp clumps of soil clinging to its roots.
⚜ Frankincense’s fragrance is earthy, woody, piney, and balsamic; with softly sweet, and citrusy notes.
⚪ This unique fragrance is 100% natural as it has been created from certified organic herbs, and is guaranteed free of any synthetic chemical or paraben.

⚜ Its sufficient to use ElixirOfYouth™ merely once in 24 hours, before going to bed at night.
⚜ Nightly application is preferred so that ElixirOfYouth™ gets absorbed through the skin, without interruptions, throughout the resting and rejuvenating phase.

⚜ Ideal for all skin types.
⚜ Men and women desiring healthy skin which reflects the beauty of eternal youth should use this serum before going to bed.
⚜ Can be used by users who are already experiencing the challenges of aging. ElixirOfYouth™ helps reverse the signs of aging, and rejuvenates the skin.
⚜ Can be use by users who haven't started experiencing signs of aging yet, as it helps prevent early onset of aging, in addition to premature aging.
⚜ Users with premature aging triggering unhealthy lifestyle (including irregular and late sleep pattern, unhealthy eating habits, smoking or consumption of a caffeinated beverages, sugared drinks, carbonated sodas or alcohol etc.), would benefit greatly from ElixirOfYouth™ because of its unbeatable anti-oxidant powers.
⚜ Ideal for users who want to eradicate dark spots, pigmentation and freckles.

BestIndian™ practices 100% transparency, and believes in disclosing all ingredients used in its products. BestIndian™ guarantees that no other ingredient, apart from those listed below, has been used in this 100% natural and synthetic chemicals free BestIndian Luxury:

⚪ Hempseed oil⚪Bakuchi oil⚪ Gotukola oil⚪Papaya seed oil⚪Black seed oil⚪Essential oils of Vetiver, Palmarosa and Frankincense.

⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to the first usage.
⚜ Best before 24 months from manufacturing.

India

⚪ During the aging process, senescent cells gradually accumulate in the organs; they secrete proinflammatory cytokines and other factors, collectively known as the senescence-associated secretory phenotype (SASP). SASP secretions contribute to “inflammaging,” which is a state of chronic, systemic, sterility, low-grade inflammatory microenvironment.
⚜ The accumulation of oxidative damage and mitochondrial dysfunction is an important factor that contributes to aging. ElixirOfYouth™ has protective effects on oxidative stress and mitochondrial function in hepatocytes. Its components have shown an antisenescence effect on human diploid fibroblasts as evidenced by a decreased expression of p16(INK4a) mRNA and senescence-associated β -galactosidase staining.

⚪ ElixirOfYouth™ ‘s ingredient P. Corylifolia’s extract treatment reduced H2O2-induced reactive oxygen species (ROS) production in HepG2 cells, inhibited ROS production in hepatocytes, and increased superoxide dismutase activity. In H2O2-treated HepG2 cells, the extract treatment recovered ATP production. PCS extract treatment recovered the oxygen consumption rate and inhibited reduction of mitochondrial membrane potential induced by oxidative stress, suggesting improvement of mitochondrial function. In addition, PCS extract treatment recovered peroxisome proliferator-activated receptor γ coactivator 1 α and carnitine palmitoyltransferase 1 mRNA and protein expression, and inhibited mitochondrial genome damage. Treatment with the major component of PCS extract, bakuchiol, also recovered mitochondrial dysfunction.
⚜ Ingredients of ElixirOfYouth™ inhibit ROS production and mitochondrial dysfunction induced by oxidative stress in hepatocytes. Reduction of inflammation of Acne skin was caused by the anti-inflammatory & antibacterial properties of ElixirOfYouth™ against Propionibacterium acnes bacteria involved in the formation of acne vulgaris. ElixirOfYouth™ stimulates the cellular activity and strengthens the protective barriers of the skin to avoid loss of moisture and collagen promoting tissues.

⚪ Bakuchiol > Retinol:
ElixirOfYouth™ contains Bakuchiol, a natural alternative to retinol, which helps address signs of ageing, such as fine lines and wrinkles, as well as improve tone and texture. Moreover, it possesses Antioxidant, Anti-inflammatory & Antibacterial properties which have been proven to reduce and control all skin-related problems and help to promote natural colour complexion and normalise individual skin pigmentation.
⚜ Bakuchiol helps renew collagen and improve skin tone and texture, and is a safer alternative to retinol for people experiencing acne, hyperpigmentation. Bakuchiol increases cell turnover, meaning it removes dead cells from our skin and renews them with new ones. The active component in Bakuchi is “Psoralens,” which produces melanin in depigmented skin when exposed to sunlight. ElixirOfYouth™ expresses similar gene expression such as improvement in fine lines, wrinkles, elasticity, firmness and reduction in photo damage without the risks involved with usage of Retinoids.

⚪ Melanin synthesis:
Melanin is a type of natural pigment that gives color to the hair, skin, and eyes in humans and animals. It is produced by specialized melanocytes which are dendritic cells located at the junction between the epidermis and the dermis and plays an important role in protecting human skin from ultraviolet (UV) lights and free radicals. However, dysregulation in melanin synthesis results in hyper pigmentary disorders, including melasma, freckles, age spots, solar lentigo, and hyperpigmentation syndromes. Melanin is synthesized from tyrosine via a multistep enzymatic process involving a number of proteins. Tyrosinase, known as the rate-limiting enzyme, is critical for melanin synthesis. Thus, to develop therapies that can improve or prevent hyper pigmentary disorders, inhibition of tyrosinase activity is generally targeted.
⚜ EtOAc fraction of ElixirOfYouth’s ingredient hemp seed extracts scavenged ABTS radicals and exhibited potent inhibitory effects on melanin biosynthesis, indicating that bioactive compounds might be abundant in this fraction. It contains vitamin F and fatty acids such as oleic and linoleic acids, which play an important role in preventing the signs of ageing on the skin and treat fine lines and wrinkles. N-trans-caffeoyltyramine exhibited the strongest potential for anti-melanogenesis activity. The inhibitory effect of N-trans-caffeoyltyramine was verified by determining the melanin content and tyrosinase activity in melanoma after treating the cells with synthetic compounds. It can be concluded that N-trans-caffeoyltyramine isolated from hemp seed extracts could be useful in cosmetics as a skin-whitening agent.

⚪ Provides a total solution for all challenges of signs of aging and loss of skin's elasticity, etc.
⚪ Collagen Boost: Stimulates collagen producing receptors in the skin to greatly boost the production of collagen to roll back years and regain youthful skin
⚪ Prevention: Prevents the appearance of wrinkles, fine lines, dark spots, pigmentation etc. by intensive skin care
⚪ Rejuvenation: Rejuvenates the skin overnight by providing intensive care and complete nourishment
⚪ Restoration: Restores the elasticity of the skin
⚪ Reduction in photo damage without the risks involved with usage of Retinoids
⚪ Stimulates the cellular activity and strengthens the protective barriers of the skin to avoid loss of moisture and collagen promoting tissues
⚪ Reduction of inflammation of Acne skin: Prevents acne flare-ups and breakouts. It balances skin's sebum production to reduce the shine, which can prevent breakouts and acne
⚪ Stimulates fibroblasts and cause an increase in collagen synthesis
⚪ Skin Tone & Brightening: Improves the skin's tone and texture
⚪ Anti-oxidant properties: Protects squalene and many skin lipids from oxidation due to its excellent antioxidant activity
⚪ Prevents dysregulation in melanin synthesis which results in hyper pigmentary disorders, including melasma, freckles, age spots, solar lentigo, etc
⚪ Solves hyperpigmentation and sun damage.
⚪ Improves the skin's hydration levels
⚪ Increases skin firmness and brings a reduction in redness, and an overall improvement in skin condition
⚪ Increases cell turnover
⚪ Herbal ⚜ Ayurvedic ⚜ Natural ⚜ Organic
⚪ 100 % FDA compliant

⚪ ElixirOfYouth™ facial serum has a mesmerizing fragrance provided by the unique symphony of Frankincense, Vetiver, and Palmarosa.
⚜ Palmarosa’s fragrance is citrusy herbaceous and metallically sweet with hints of rose.
⚜ Vetiver’s scent is earthy and woody with notes of freshly cut grass and blended citrus on a warm day, with damp clumps of soil clinging to its roots.
⚜ Frankincense’s fragrance is earthy, woody, piney, and balsamic; with softly sweet, and citrusy notes.
⚪ This unique fragrance is 100% natural as it has been created from certified organic herbs, and is guaranteed free of any synthetic chemical or paraben.

⚜ Its sufficient to use ElixirOfYouth™ merely once in 24 hours, before going to bed at night.
⚜ Nightly application is preferred so that ElixirOfYouth™ gets absorbed through the skin, without interruptions, throughout the resting and rejuvenating phase.

⚜ Ideal for all skin types.
⚜ Men and women desiring healthy skin which reflects the beauty of eternal youth should use this serum before going to bed.
⚜ Can be used by users who are already experiencing the challenges of aging. ElixirOfYouth™ helps reverse the signs of aging, and rejuvenates the skin.
⚜ Can be use by users who haven't started experiencing signs of aging yet, as it helps prevent early onset of aging, in addition to premature aging.
⚜ Users with premature aging triggering unhealthy lifestyle (including irregular and late sleep pattern, unhealthy eating habits, smoking or consumption of a caffeinated beverages, sugared drinks, carbonated sodas or alcohol etc.), would benefit greatly from ElixirOfYouth™ because of its unbeatable anti-oxidant powers.
⚜ Ideal for users who want to eradicate dark spots, pigmentation and freckles.

BestIndian™ practices 100% transparency, and believes in disclosing all ingredients used in its products. BestIndian™ guarantees that no other ingredient, apart from those listed below, has been used in this 100% natural and synthetic chemicals free BestIndian Luxury:

⚪ Hempseed oil⚪Bakuchi oil⚪ Gotukola oil⚪Papaya seed oil⚪Black seed oil⚪Essential oils of Vetiver, Palmarosa and Frankincense.

⚜ Store in a cool and dry place, away from direct sunlight.
⚜ For external use only.
⚜ Reading the ingredients list is recommended to ensure that the user is not allergic to any ingredient herb.
⚜ Patch test is recommended on a small area of the skin prior to the first usage.
⚜ Best before 24 months from manufacturing.

India

⚪ During the aging process, senescent cells gradually accumulate in the organs; they secrete proinflammatory cytokines and other factors, collectively known as the senescence-associated secretory phenotype (SASP). SASP secretions contribute to “inflammaging,” which is a state of chronic, systemic, sterility, low-grade inflammatory microenvironment.
⚜ The accumulation of oxidative damage and mitochondrial dysfunction is an important factor that contributes to aging. ElixirOfYouth™ has protective effects on oxidative stress and mitochondrial function in hepatocytes. Its components have shown an antisenescence effect on human diploid fibroblasts as evidenced by a decreased expression of p16(INK4a) mRNA and senescence-associated β -galactosidase staining.

⚪ ElixirOfYouth™ ‘s ingredient P. Corylifolia’s extract treatment reduced H2O2-induced reactive oxygen species (ROS) production in HepG2 cells, inhibited ROS production in hepatocytes, and increased superoxide dismutase activity. In H2O2-treated HepG2 cells, the extract treatment recovered ATP production. PCS extract treatment recovered the oxygen consumption rate and inhibited reduction of mitochondrial membrane potential induced by oxidative stress, suggesting improvement of mitochondrial function. In addition, PCS extract treatment recovered peroxisome proliferator-activated receptor γ coactivator 1 α and carnitine palmitoyltransferase 1 mRNA and protein expression, and inhibited mitochondrial genome damage. Treatment with the major component of PCS extract, bakuchiol, also recovered mitochondrial dysfunction.
⚜ Ingredients of ElixirOfYouth™ inhibit ROS production and mitochondrial dysfunction induced by oxidative stress in hepatocytes. Reduction of inflammation of Acne skin was caused by the anti-inflammatory & antibacterial properties of ElixirOfYouth™ against Propionibacterium acnes bacteria involved in the formation of acne vulgaris. ElixirOfYouth™ stimulates the cellular activity and strengthens the protective barriers of the skin to avoid loss of moisture and collagen promoting tissues.

⚪ Bakuchiol > Retinol:
ElixirOfYouth™ contains Bakuchiol, a natural alternative to retinol, which helps address signs of ageing, such as fine lines and wrinkles, as well as improve tone and texture. Moreover, it possesses Antioxidant, Anti-inflammatory & Antibacterial properties which have been proven to reduce and control all skin-related problems and help to promote natural colour complexion and normalise individual skin pigmentation.
⚜ Bakuchiol helps renew collagen and improve skin tone and texture, and is a safer alternative to retinol for people experiencing acne, hyperpigmentation. Bakuchiol increases cell turnover, meaning it removes dead cells from our skin and renews them with new ones. The active component in Bakuchi is “Psoralens,” which produces melanin in depigmented skin when exposed to sunlight. ElixirOfYouth™ expresses similar gene expression such as improvement in fine lines, wrinkles, elasticity, firmness and reduction in photo damage without the risks involved with usage of Retinoids.

⚪ Melanin synthesis:
Melanin is a type of natural pigment that gives color to the hair, skin, and eyes in humans and animals. It is produced by specialized melanocytes which are dendritic cells located at the junction between the epidermis and the dermis and plays an important role in protecting human skin from ultraviolet (UV) lights and free radicals. However, dysregulation in melanin synthesis results in hyper pigmentary disorders, including melasma, freckles, age spots, solar lentigo, and hyperpigmentation syndromes. Melanin is synthesized from tyrosine via a multistep enzymatic process involving a number of proteins. Tyrosinase, known as the rate-limiting enzyme, is critical for melanin synthesis. Thus, to develop therapies that can improve or prevent hyper pigmentary disorders, inhibition of tyrosinase activity is generally targeted.
⚜ EtOAc fraction of ElixirOfYouth’s ingredient hemp seed extracts scavenged ABTS radicals and exhibited potent inhibitory effects on melanin biosynthesis, indicating that bioactive compounds might be abundant in this fraction. It contains vitamin F and fatty acids such as oleic and linoleic acids, which play an important role in preventing the signs of ageing on the skin and treat fine lines and wrinkles. N-trans-caffeoyltyramine exhibited the strongest potential for anti-melanogenesis activity. The inhibitory effect of N-trans-caffeoyltyramine was verified by determining the melanin content and tyrosinase activity in melanoma after treating the cells with synthetic compounds. It can be concluded that N-trans-caffeoyltyramine isolated from hemp seed extracts could be useful in cosmetics as a skin-whitening agent.